In terms of nightlife, the Gaslamp is probably the place to be. Just wander around on foot and you will find plenty of good bars and clubs. Depending on where you are staying, you may be close to the trolley if TJ appeals to you, as it will take you right to the border. For daytime fun there’s always the beach or beaches as may be more accurate.
If you like baseball, the Padre’s are in season and a short trolley ride away from the downtown. If you like expensive stuff or gawking at trophy wives with large implants, there’s always La Jolla. If you like looking at large implants in general, there are a few decent quality nudy bars in the area, as well as some crappy ones. On a related note, their are several indian casinos within about 45 min and they aren’t bad.
It occurs to me that despite the fact that I’ve been going to school here for a while, I really don’t know what to do in my spare time. That may be because I don’t seem to have any. This quarter’s book stack for school is measuring 25.5" so far-- that’s the price of a nerd school I suppose. Enough of my problems.
This is really depressing me now sorry I couldn’t be of greater help.