I have often consumed red wine for its supposed health benefits, not because I particularly like red wine. However, recently I decided to look at resveratrol concentrations in red wine compared with REZ-V, since supposedly much of the health benefits of red wine is believed to come from the chemical. I was pretty surprised at what I found–if you were to drink a liter of Spanish red wine every day, you would be getting, at most, 12.59mg of resveratrol per day (not to mention pretty wasted). In contrast, REZ-V contains 600mg of resveratrol.
Why is this absurdly high dose necessary or even healthy? If benefits can be had at the 2-6mg levels (which is what a regular drinking of quality wines would be getting), why is the 100x that better.
Now the blurb accompanying REZ-V states that:
[quote]It’s best to take one large dose of resveratrol, instead of several smaller doses, because of the way it’s metabolized. In essence, you want to overwhelm the body’s ability to inactivate and excrete resveratrol, which is done through sulfation and glucuronidation (adding sulfate and beta-glucuronide groups).
This “overwhelming” process is accomplished at about 200 mg taken in one shot. A three-capsule dose contains 600 mg of pure resveratrol, which is also the dose we believe delivers the greatest benefit for the least cost.[/quote]
But if this was true, how would around 6mg per day account for the so-called “French Paradox”. Such an extreme dose seems wasteful at best, and dangerous at worst.