T Nation

Resveratrol and Joint Pain

Hello all,

I started taking resveratrol last week at 425 mg/day as an AI to accompany the d-aspartic acid that I’ve been taking in cycles for the last several months. The latter supplement has namely been presumed to indirectly increase T levels by stimulating LH production in the pituitary.

Luckily, I’ve felt as though I’ve had positive results from the d-aspartic acid, although I am aware that the estrogen-raising characteristics of such a supplement should be counteracted using an AI. Apart from resveratrol, I take ca. 30 g zinc gluconate per day.

Last Friday I began noticing pain in my left trap, which has since spread around to my shoulders/upper back and into my knees. Since I haven’t modified my training programme at all for the last few weeks, I assume that: a) I’ve not had enough quality sleep in the last few days; or b) the resveratrol (possibly in combination with the zinc) has reduced my estrogen to microscopic levels, thus leading to joint pain.

Have any of you had similar experiences with resveratrol or with (over-the-counter) AIs in general? Would you recommend lowering the dosage, switching to another AI or simply laying off the AIs and seeing what happens?

Thanks!

Bump… No ideas here? I’ve looked into a few other internet forums about the same topic and have found a few incidences of joint pain, although the forum members seemed to be mostly older individuals and many were taking a good number of rather eccentric supplements.

I don’t know about using DAA or reservatrol or zinc like that, but high[er] dosage fish oil seems to work very well for a lot of people.

Personally, I take a tablespoon of liquid fish oil a day, which provides 2400mg EPA and 1500mg DHA (3900mg total EPA/DHA).

That’s about the same as 6g of good OTC fish oil capsules, or 5 Flameout capusles (minus the CLA isomers).

I’m using about 6 g of EPA/DHA per day in the form of high-concentrated capsules. The Biotest stuff is here in Europe pretty expensive and hard to come across.

The joint pain is, of course, not my main conceern, but rather the fact that my estrogen levels might be near null, which of course has an array of other consequenses. Good point, though; I might try upping the dosage of EPA/DHA and lowering the resveratrol.

Would the lower dosage of resveratrol still, however, be enough to serve as an AI? Isn’t Rez-V, for example, supposed to be taken in one dose in order to be assimilated correctly in order to have anti-estrogenic qualities?

[quote]kgildner wrote:
Hello all,

I started taking resveratrol last week at 425 mg/day as an AI to accompany the d-aspartic acid that I’ve been taking in cycles for the last several months. The latter supplement has namely been presumed to indirectly increase T levels by stimulating LH production in the pituitary.

Luckily, I’ve felt as though I’ve had positive results from the d-aspartic acid, although I am aware that the estrogen-raising characteristics of such a supplement should be counteracted using an AI. Apart from resveratrol, I take ca. 30 g zinc gluconate per day.

Last Friday I began noticing pain in my left trap, which has since spread around to my shoulders/upper back and into my knees. Since I haven’t modified my training programme at all for the last few weeks, I assume that: a) I’ve not had enough quality sleep in the last few days; or b) the resveratrol (possibly in combination with the zinc) has reduced my estrogen to microscopic levels, thus leading to joint pain.

Have any of you had similar experiences with resveratrol or with (over-the-counter) AIs in general? Would you recommend lowering the dosage, switching to another AI or simply laying off the AIs and seeing what happens?

Thanks![/quote]
I took one tablet of

[quote]kgildner wrote:
Hello all,

I started taking resveratrol last week at 425 mg/day as an AI to accompany the d-aspartic acid that I’ve been taking in cycles for the last several months. The latter supplement has namely been presumed to indirectly increase T levels by stimulating LH production in the pituitary.

Luckily, I’ve felt as though I’ve had positive results from the d-aspartic acid, although I am aware that the estrogen-raising characteristics of such a supplement should be counteracted using an AI. Apart from resveratrol, I take ca. 30 g zinc gluconate per day.

Last Friday I began noticing pain in my left trap, which has since spread around to my shoulders/upper back and into my knees. Since I haven’t modified my training programme at all for the last few weeks, I assume that: a) I’ve not had enough quality sleep in the last few days; or b) the resveratrol (possibly in combination with the zinc) has reduced my estrogen to microscopic levels, thus leading to joint pain.

Have any of you had similar experiences with resveratrol or with (over-the-counter) AIs in general? Would you recommend lowering the dosage, switching to another AI or simply laying off the AIs and seeing what happens?

Thanks![/quote]
I took one tablet of MAX Resveratrol saturday

[quote]kgildner wrote:
Hello all,

I started taking resveratrol last week at 425 mg/day as an AI to accompany the d-aspartic acid that I’ve been taking in cycles for the last several months. The latter supplement has namely been presumed to indirectly increase T levels by stimulating LH production in the pituitary.

Luckily, I’ve felt as though I’ve had positive results from the d-aspartic acid, although I am aware that the estrogen-raising characteristics of such a supplement should be counteracted using an AI. Apart from resveratrol, I take ca. 30 g zinc gluconate per day.

Last Friday I began noticing pain in my left trap, which has since spread around to my shoulders/upper back and into my knees. Since I haven’t modified my training programme at all for the last few weeks, I assume that: a) I’ve not had enough quality sleep in the last few days; or b) the resveratrol (possibly in combination with the zinc) has reduced my estrogen to microscopic levels, thus leading to joint pain.

Have any of you had similar experiences with resveratrol or with (over-the-counter) AIs in general? Would you recommend lowering the dosage, switching to another AI or simply laying off the AIs and seeing what happens?

Thanks![/quote]
I too

I took resveratrol the very next day my shoulder and neck were fu&ked thinking i over did it a work kept t

From day one this stuff gave me pain thinking i over worked kept taking it 8 days later and a shit load of painkillers later for sore shoulder,elbow and knee all on the right side,hope stopping with

Resveratrol is known to block absorption of minerals, especially iron. In some cases, high intake can cause anemic symptoms. Furthermore, high levels of individual antioxidants can actually have an oxidant effect. Both could cause joint pain, and I would guess that either one of these would be much more likely than completely crashed estrogen levels.

^ Interesting explanation, thanks.

I’ve stopped taking Resveratrol for the time being. I’m going to continue to cycle DAA on a one month on/one week off basis (I’ve found that to be pretty good for refreshing my body’s sensitivity to the supplement, if that makes any sense) and try to get some blood work done some time in the near future at the tail end of a cycle. If my E2 levels are under control, I wouldn’t see any need to throw in an AI as it is. I’ve never had any real issues with fat storage or such, and previous blood panels have revealed lowish E2 levels anyways.

I’m interested in this-- can someone explain to me how exactly resveratrol affects the joints that can result in pain? This is definitely the first time I have heard this…

In terms of helping it – have you tried MSM? I started taking it in conjuction with vitamin C and my joints have never felt better…