Honestly, I don’t even know if we know precisely what leads to adjusting your body fat setpoint. Furthermore, it’s not a magic bullet either. It’s not like it prevents you from getting fat.
I’m not sure if changing your setpoint means what you think it means, or what you want it to be.
Changing your setpoint doesn’t prevent you from gaining fat. If you eat a surplus, you will gain fat.
The main effect of lowering your setpoint is lowering “unnecessary hunger/cravings”. See, the further away you are (lower) from your bodyfat set point, the more cravings you get (it has to do with both lowered leptin levels and an increase in dopamine sensitivity which increases the pleasure response to “pleasure foods”). And that’ the thing: if you are a lot lower than your setpoint, even if you eat at maintenance or a slightly surplus, you will still get these cravings, that’s why most people yo-yo when dieting.
Lowering your setpoint essentially makes it less likely that you will get these cravings, making it mentally and physically easier to feel satisfied with maintenance eating and less prone to binging.
For example if your setpoint is 20% and you are down to 10%. Your leptin will be low and your cravings will be monstruous. Food will be your main thought most of the time.
Now, if your setpoint is 12%, and you are down to 10%. It will be easy to maintain as you don’t get huge cravings and are much less likely to binge out.
Now, you might be able to handle a bit more food when your setpoint is lower, mostly carbs, because it comes with a better glucose tolerance and insulin sensitivity. But it doesn’t turn you into one of those dudes who can eat whatever they want and stay thin.
Last year I “bulked up” to bring my squat back up to over 500lbs. I went from 210 to 231 and I gained fat just like anybody else. BUT that’s because I was forcing myself to eat. My lower setpoint made food repulsive as soon as I got significantly higher than my setpoint.
I can only speak for myself, as I don’t know many people who have successfully adjusted their set-point.
I think that I’ve done it as I can stay fairly lean (full abdominal definition) without much effort. As I said, last year I actually tried to “eat big to get stronger” and I quickly hit a point where my body simply made me hate food, past a certain body fat level, I just couldn’t eat.
Anyway, I want to start by saying that there is no pill that you can take that will automatically give you a lower set-point. I know that TC wrote about Indigo 3G helping, and it will. But it’s not a magic bullet. It does improve insulin sensitivity, which will improve nutrients partitioning (sending more of what you eat to the muscles rather than fat cells) but it’s not like you can take it, eat anything and stay lean.
From my own experience, and the few people that I’m aware of who did adjust their set-point, it is a long process and it requires a lot of discipline. So don’t look at this like “cool, once my setpoint is adjusted I’ll be able to eat whatever I want and stay lean”… you actually need to be structured and very conscious about the types of food you eat for as long as possible for the adjustment to occur.
Here’s what I think helped me the most:
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Time at a low body fat: The absolute most important factor when it comes to adjusting your setpoint is spending A LONG time at a low(er) body fat level. Think about it; if you spend 10 years at 20% or more, spending 2 weeks at 10% will do nothing to adjust your setpoint. You need to spend months and probably years to truly adjust your setpoint. That’s why I say it takes discipline. I personally stayed at 10% or lower for 3-4 years through not consuming a surplus for more than a few days per month. You cannot change something that was “installed” and solidified in several years by dong something different for 2-3 months.
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Increasing Energy Flux (G-Flux): this is a concept that originated with Dr. Berardi (you can find the articles on T-nation). It basically means having a more important energy turnaround: ingesting more energy (food, calories) BUT also expending a lot more energy. For example, let’s say that your daily energy intake is 2000kcals and your daily expenditure is 2000kcals. You are eating at maintenance because you are spending the same amount as you are ingesting. But it’s a LOW energy flux. If you ingest 3750kcals/day and spend the same 3750kcals, you are still eating at maintenance, but you now have a HIGH energy flux. There is plenty of evidence showing that this could be very helpful to reset your setpoint once you are already lean.
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Reduce chronic systemic inflammation: systemic inflammation has tons of negative effects. But when it comes to the topic at hand, the most important is that it reduces glucose tolerance/insulin sensitivity. This, in-turn has a negative impact on nutrients partitioning (more likely to store nutrients as fat instead of in the muscles). Processed foods are pro-inflammatory. High sugar foods are pro-inflammatory. Foods high in omega-6 fatty acids are pro-inflammatory. So you need to limit those, if not drop them completely.
Those who successfully change their setpoint are essentially people who change their lifestyle, especially their nutrition. That’s why I say that if your goal is to be able to eat whatever you want and not gain fat, you will never be able to change your setpoint as changing your setpoint requires:
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Avoiding all processed and high sugar foods.
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Eating at maintenance level for a long time, to maintain a low(er) body fat level for as long as possible. At the very least you’ll need to stay at a low(er) body far level for at least a year to have a chance at changing your setpoint.
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Increase the amount of calories that constitute “maintenance” by increasing daily energy expenditure by a lot.
YES supplements like Indigo 3G will help, and so will omega-3 fatty acids and curcumin for their anti-inflammatory effects. But it wont be enough if you don’t apply points 1-3 too.
I KNOW it’s not the answer you wanted to hear. But it is the correct one and now you understand why few people are successful at changing their setpoint.
It is also my belief that yoyoing makes it a lot less likely that you will successfully change your set point because the more often you do it, the more you program your body to rebound up as soon as your body fat levels get lower.