T Nation

Question for Bill or Brock: Methylated 4-AD


#1
 Androstenediol is a natural dietary supplement that works well for most users. However, it would be extremely powerful if an alkyl substitute was added to the product. This methylated version would basically be the same thing as methyandrostenediol, which is also called Methandriol. I know that this modification would increase the toxicity of the supplement, but I was wondering why no company has tried manufacturing 4-AD in this manner. Is it a legal concern, a technical one, or both? This product would rule if it could be sold as a dietary supplement.

#2

It wouldn't be the same as methandriol,
since the double bond is in a different
position. But you're right, oral activity
would be improved.

It would not be legal as a supplement because
it is neither naturally occuring nor a
precursor of one. E.g., you can make an
ester of a naturally occurring compound
for example a vitamin, and that's perfectly
OK even though the ester version does
not occur in nature. It's recognized
that you can make a modified version that
converts in the body to the natural
compound. However, the 17-methyl will not
be removed by the body and the compound
you describe would have to be considered
a synthetic drug or unapproved drug.


#3

uhh yea dude you can't have any non drug akylated.