T Nation

Question about HPTA Restart?

Took a while but i’ve finally started the HPTA Restart protocol recommended by KSman. I’m on my 5th week of the 250iu/EOD HCG phase…and I feel ZERO difference. I know i won’t know for sure till i do blood work…but ZERO?? Is that normal…to feel no difference, if the restart is a success? That’s one question. The other questions…

  1. I’m injecting 0.1 cc (which equals to 250iu HCG - 5000iu powder HCG reconstituted with 2cc bac water. I draw from it 0.1cc every other day) using a 0.5cc BD insulin syringe on belly fat. Is this OK? Or is the syringe/needle to small? And what about the reconstitution (0.1cc)…is that too small it be effective?

  2. Since KSman’s HPTA Restart Protocol in the stickies…has there been updated/revised protocols? Or is this still the gold standard? Just curious in case this doesn’t work.

* 1cc=1ml

  1. you are doing everything OK. Is this hCG from a pharmacy? If good, will be positive on a home pregnancy test.

  2. nothing has changed, but there is now a strong focus on thyroid and iodine issues.

Standard stuff…
Please read the stickies found here: About the T Replacement Category

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

KSman is simply a regular member on this site. Nothing more other than highly active.

I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.

The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.

Hypothetical question: Are there any side effects if i continue the HCG protocol for 11 weeks instead of 4-6?


I used the restart protocol myself, and I have a log here documenting the results. No issues running longer but you mentioned you feel zero results. You should try bumping to 500 IU EOD and make sure you take an aromatase inhibitor. Assuming you are not primary hypogondadal that amount should jack your Testosterone quite a bit. There is no need to run longer than three weeks or so at that amount. If the HCG is legit you will feel a difference by the end of the first week. Then, switch to a low dose serm and retest your levels six weeks after your last serm dose.