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Question About Digestive Enzymes

I was wondering, do the digestive enzymes protease, amylase and lipase only help with digestion when taken directly with (or right before) a meal or do you build up on these enzymes so that after a while your natural digestion is improved?

Thanks in advance.

I’m pretty sure that they only work with the meal.

As soon as they leave the capsule, they look for their respective molecules to digest. If there is no work to be done, they are excreted or destroyed. That is my understanding of it.