T Nation

Pubertal Gyno

I’ve just turned 18, and had it for about two years. According to most of the literature I’ve read, if it were to clear up on its own, it probably would have done so by now. I’ve decided to get as proactive as I can about this.

I’m going to the doc’s office at the end of the week and am going to see if he’ll write me a prescription for some Arimidex or tomoxifen, as I’ve read positive things about these.

Anybody ever been here? Any advice?

[quote]Dango wrote:
I’ve just turned 18, and had it for about two years. According to most of the literature I’ve read, if it were to clear up on its own, it probably would have done so by now. I’ve decided to get as proactive as I can about this.

I’m going to the doc’s office at the end of the week and am going to see if he’ll write me a prescription for some Arimidex or tomoxifen, as I’ve read positive things about these.

Anybody ever been here? Any advice?[/quote]

I think you need to accept the fact that you will probably need surgery to get rid of it. This problem affects somewhere around 60% of all males in this country. That means most of the guys you have known have had it to some degree. Like you, most won’t throw off their shirt in public to draw attention to it. Add to that the fact that you have to have a relative lower body fat percentage for it to be visible outside of simply being fat and you have many who won’t even ever know they have it. The drugs you mentioned are usually useful when it is first beginning.

Arimidex or tamoxifen as far as I know wont eliminate Gyno that is already developed. Unfortunately the only true way to get rid of it is surgery.

However, you can try the above meds and see what they do… Although don’t expect them to do much.

Well, thanks for the help.

Guess I’ll start pinching my pennies.

I had this off and on when I was in my teens, then it disappeared around 17 or 18, and one day came back when I was in 22…and is still here. It’s small enough where I probably won’t get the surgery unless I find myself loaded with cash some day.

uhm i beg to differ…even tho this is an old post check this out.
Your doctor may or may not have heard about this treatment. Show him this, so he’ll know its safe:

http://www.ncbi.nlm.nih.gov/entrez/q…&dopt=Abstract

Horm Res. 2002;57(5-6):187-91. Related Articles, Links

Effects of tamoxifen on lipid profile and coagulation parameters in male patients with pubertal gynecomastia.

Novoa FJ, Boronat M, Carrillo A, Tapia M, Diaz-Cremades J, Chirino R.

Department of Endocrinology, Hospital Universitario Insular, Las Palmas de Gran Canaria, Spain. jnovoa@cicei.ulpgc.es

BACKGROUND/AIM: The estrogenic actions of tamoxifen on lipid profiles and hemostasis have been extensively demonstrated in women. Due to limited experience with this drug in males, it is uncertain whether these effects are also present in men. The aim of our study was to assess the response of blood lipids, lipoproteins, and coagulation parameters in a group of men taking tamoxifen. METHODS: We studied 15 healthy boys with pubertal gynecomastia who were given 10 mg tamoxifen per day. Total testosterone, sex-hormone-binding globulin, estradiol, serum lipids, apolipoprotein B, apolipoprotein A-I, lipoprotein(a), fibrinogen, antithrombin III, von Willebrand factor, and markers of activated coagulation and fibrinolysis were determined at baseline and 1 and 3 months after beginning of the tamoxifen treatment. RESULTS: Total cholesterol and lipoprotein(a) showed moderate but significant decreases from baseline. Low-density lipoprotein and high-density lipoprotein cholesterol concentrations as well as triglyceride and apolipoprotein B levels became lower, but these changes were not statistically significant. Among clotting parameters, antithrombin III was reduced, and von Willebrand factor increased significantly. Markers of activated coagulation and fibrinolysis remained unchanged throughout the period of therapy. CONCLUSIONS: The effects of tamoxifen on blood lipids and hemostasis we found in this group of healthy young men were qualitatively similar, but lesser than those previously described in women. Copyright 2002 S. Karger AG, Basel

Then show him this so he’ll give you the nolvadex:

http://www.ncbi.nlm.nih.gov/entrez/q…&dopt=Abstract

Klin Padiatr. 1987 Nov-Dec;199(6):389-91. Related Articles, Links

[Treatment of marked gynecomastia in puberty with tamoxifen]

[Article in German]

Konig R, Schonberger W, Neumann P, Benes P, Grimm W.

Kinderklinik, Universitat Mainz.

Based on the good results of another author 10 boys with marked pubertal gynecomastia were treated with the antioestrogen Tamoxifen (Nolvadex) at a dose of 20-40 mg/d orally for 2-12 months. In most cases the gynecomastia decreased totally, only two patients experienced palpable subareolar glandular tissue at the end of therapy. Side effects were not noted. During therapy levels of estradiol and testosteron increased, with a more pronounced elevation of estradiol. Basal values of LH and FSH remained nearly unchanged, but LH showed an increased response to LH-RH, which could be explained by the antioestrogenic effect of Tamoxifen at the hypothalamic level. The reduction of breast size in spite of increased estradiol levels on the other hand, suggests that the mean therapeutic effect of tamoxifen is through estrogen receptor blockade of breast tissue.

and this…

http://www.ncbi.nlm.nih.gov/entrez/q…&dopt=Abstract

Dtsch Med Wochenschr. 1984 Nov 2;109(44):1678-82. Related Articles, Links

[Testosterone and estradiol levels in male gynecomastia. Clinical and endocrine findings during treatment with tamoxifen]

[Article in German]

Eversmann T, Moito J, von Werder K.

Oestradiol-(E2) levels in serum were significantly higher in a group of 91 males with gynaecomastia than in a control group. The levels were highest in patients with testicular tumour, hyperprolactinaemia and idiopathic gynaecomastia. In gynaecomastia of puberty and primary or secondary hypogonadism, the E2 level was within normal limits, but the testosterone/oestradiol ratio was significantly reduced. Tamoxifen, at a daily dose of 20 mg, was administered over 2-4 months to 16 patients with gynaecomastia. Of twelve patients with painful gynaecomastia ten became painfree. Gynaecomastia regressed partially or completely in 14 patients, in only 2 was it unchanged. There was no recurrence of gynaecomastia after discontinuing tamoxifen. Side-effects did not occur. It is concluded that tamoxifen is a promising alternative to the surgical treatment of gynaecomastia.

Good post Facko. Thanks for the info.