It's pretty much been proven that the greater the protein degradation from training the higher the protein synthesis and therefore strength and hypertrophy increases. (provided you don't overtrain).
It's also been proven that the greater the load the greater the protein degradation. The only reason Lifting with 3 or less reps/set isn't good for hypertrophy is the limited time under the large load isn't sufficient for optimal protein degradation. That's why Waterbury's 10x3 is so good.
You get the best of both worlds, 30 reps total at very high loads = significant degradation and therefore synthesis and growth.
My question is about the law of fiber recruitment where your muscles only contract as hard as required to lift a load. The closer to failure the better chance all your fibers are contracting.
Would this result in greater protein degradation or is closeness to failure irrelevant when lifting over 80% max for fiber recruitemnt? Would 6 sets of 5 to failure be better than 10 sets of 3 with the same weight not to failure?
I may be way off, just looking for feedback.