Anabolics shut down natural steroid production. Is that the production of testosterone, or the production of all steroids, from cholesterol? My guess is that all steroid production is shut down to some extent. Progesterone is one of the first steroids in the chain of hormone metabolism. Progesterone counters the effects of prolactin, in terms of milk production anyway, so maybe it’d help with tren side effects.
The metabolites of progesterone also have mild anti-seizure activity. Supplementing with progesterone so that it’s at a normal level might help with some anabolics’ side effects. Studies have shown that progesterone causes an antiseizure effect because it’s a prohormone to allopregnanolone. I’d worry about taking too much, then stopping, and then having a higher seizure potential, but studies have shown allopgrenanolone does not cause tolerance. It would also be only to normalize hormone levels, since taking anabolics, I’m sure, lowers pregnanolone. Studies have proven it requires metabolization in order to be effective, it’s be tough to push neuroactive hormones over physiological doses through low dose progesterone supplementation.
Progesterone supplementation seems like it’s actually common for women, there are all sorts of inexpensive creams and vitamins, and there haven’t been any serious side effects, serious enough to keep progesterone from being sold OTC. Can it have adverse side effects in men, though? I thought it was a female-ish hormone. It’s marketed to women, but I don’t see why men can’t take it, and if it’s taken with a low dose of letro or proviron, there wouldn’t be an increase in estrogen.
Can progesterone decrease some of the steroid side effects, or is it a bad idea?