I don’t think that overuse of a computer or anything else is sufficient to cause something like CTS. I believe it’s always overuse plus poor postural mechanics plus excessive tension. It’s like a car that’s out of alignment. If you never drive it, or you drive very little and very slowly, the bad alignment won’t cause any problems. It’s when you drive it a lot that you see the signs of excessive and uneven wear. Yes, driving does contribute to the wear, but the damage is excessive and uneven because of the bad alignment.
Sonny, to reiterate, if you want to prevent CTS, make sure that your whole musculo-skeletal system is healthy and aligned properly. Ian King’s and Mike Robertson’s articles are a good start for self-diagnosis, and ART practitioners should be helpful for this, too. If you have excessive kyphosis, for example, plus do a lot of computer work or other hand/wrist intensive movements, you are at risk for CTS.
I suffered severely from cubital tunnel syndrome several years ago. Now I’m completely recovered (from that condition) and use a computer more than ever with no problems whatsoever.