Going to try to keep this short Last November I was under chronic stress, a month later started having hard crashes mid-day. My GP in March '12 pulled my test which came back low. I was put on gels for 6 months that did not work, lower and higher doses T dropped lower, E2 went higher. I was moved to test cyp shots 1w 100mg, Test went up over 700, but so did my SHBG FT and E2 to HIGH levels, I have since been lowering my dose and splitting the injections to twice a week to try to control my E2, No AI at this point and still feel horrible.
I noticed though after taking my shot within a few hours I feel dazed, tired like I had taken a strong allergy pill, stoned (at doses higher then 30mg I feel constant stress, adrenaline) . The dazed state would last for up to 24 hours depending on my dose and after about 3 days I would start feeling OK again.
After hours and hours of researching I only found the following, I was hoping maybe someone might be able to help or might of had the same issue could direct me to a possible cause
1.) Test Cyp Allergy to Cottonseed Oil
2.) Testosterone is lowering Thyroid
3.) Adrenals to weak to handle Test
Here are my Labs:
Result: 12/28/2011
CMP with Est GFR
Sodium 141 135-145 mEq/L
Potassium 5.0 3.5-5.3 mEq/L
Chloride 101 96-112 mEq/L
C02 28 19-32 mEq/L
Glucose 94 70-99 mg/dL
BUN 10 6-23 mg/dL
Creatinine 0.98 0.40-1.50 mg/dL
Bilirubin, Total 0.3 0.3-1.2 mg/dL
Alkaline Phosphatase 96 39-117 U/L
AST/SGOT 13 0-37 U/L
ALT/SGPT 14 0-53 U/L
Total Protein 7.9 6.0-8.3 g/dL
Albumin 5.1 3.5-5.2 g/dL
Calcium 10.1 8.4-10.5 mg/dL
CBC With Diff
WBC 8.6 4.0-10.5 K/uL
RBC 5.16 4.22-5.81 MIL/uL
Hemoglobin 15.8 13.0-17.0 g/dL
Hematocrit 46.9 39.0-52.0 %
MCV 90.9 78.0-100.0 fL
MCH 30.6 26.0-34.0 pg
MCHC 33.7 30.0-36.0 g/dL
RDW 12.8 11.5-15.5 %
Platelet Count 418 150-408 K/ul.
Granulocyte 63 43-77 %
Absolute Gran 5.5 1.7-7.7 K/uL
Lymph % 28 12-46%
Absolute Lymph 2.4 0.7-4.0 K/uL
Mono % 8 3-12 %
Absolute Mono 0.7 0.1-1.0 K/uL
Eos % 1 0-5 %
Absolute Eos 0.1 0.0-0.7 K/uL
Baso % 0-1 %
Absolute Baso 0.0 0.0-0.1 K/uL
TSH 1.421 0.350-4.500 uIU/ml
Free T4 1.45 0.80-1.80 ng/dl
Vitamine B12 355 211-911 pg/mL
Hemoglobin A1C 5.5 <5.7 %
Est Avg Glucose 111 <117 mg/dL
Vitamin D 37 30-89 ng/mL
Result:3/15/2012
CMP with Estimated GFR
Sodium 140 135-145 mEq/L
Potassium 4.6 3.5-5.3 mEq/L
Chloride 101 96-112 mEq/L
C02 25 19-32 mEq/L
Glucose 89 70-99 mg/dL
BUN 13 6-23 mg/dL
Creatinine 0.99 0.40-1.50 mg/dL
Bilirubin, Total 0.4 0.3-1.2 mg/dL
Alkaline Phosphatase 83 39-117 U/L
AST/SGOT 16 0-37 U/L
ALT/SGPT 22 0-53 U/L
Total Protein 7.4 6.0-8.3 g/dL
Albumin 5.1 3.5-5.2 g/dL
Calcium 9.7 8.4-10.5 mg/dL
CBC With Diff
WBC 6.6 4.0-10.5 K/uL
RBC 4.88 4.22-5.81 MIL/uL
Hemoglobin 15.0 13.0-17.0 g/dL
Hematocrit 44.7 39.0-52.0 %
MCV 91.6 78.0-100.0 fL
MCH 30.7 26.0-34.0 pg
MCHC 33.6 30.0-36.0 g/dL
RDW 13.6 11.5-15.5 %
Platelet Count 338 150-400 K/ul.
Granulocyte 51 43-77 %
Absolute Gran 3.4 1.7-7.7 K/uL
Lymph % 37 12-46 %
Absolute Lymph 2.5 0.7-4.0 K/uL
Mono % 9 3-12 %
Absolute Mono 0.6 0.1-1.0 K/uL
Eos % 3 0-5 %
Absolute Eos 0.2 0.0-0.7 K/uL
Baso % 0-1 %
Absolute Baso 0.0 0.0-0.1 K/uL
Sed Rate 6 0-16 mm/hr
Lipid Profile
Cholesterol 243 0-200 mg/dL
Triglyceride 230 <150 mg/dl
HDL 45 >39 mg/dL
Ttl Chol/HDL Ratio 5.4
VLDL 46 0-40 mg/dl
LDL 152 0-99 mg/dl
TSH 2.070 0.350-4.500 uIU/ml
Testosterone, Total 218.84 250-890
Vitamine B12 354 211-911 pg/mL
Hemoglobin A1C 5.5 <5.7 %
Est Avg Glucose 111 <117 mg/dL
Vitamin D 37 30-89 ng/mL
Results 5/15/2012
DHEAS (saliva) 28.2 2-23 ng/ml
CORTISOL Morning (saliva) 5.8 ng/ml 3.7-9.5
CORTISOL Noon (saliva) 2 ng/ml 1.2-3.0
CORTISOL Evening (saliva) 0.9 ng/ml 0.6-1.9
CORTISOL Night (saliva) 0.6 ng/ml 0.4-1.0
Results 5/16/2012
FSH/LH/Testosterone
FSH 3.9 1.6-8.0 mIU/mL
LH 2.3 1.5-9.3 mIU/mL
PROLACTIN 7.4 2.0-18.0 ng/mL
CORTISOL, A.M. 10.4 4.0-22.0 mcg/dL
ACTH, PLASMA 9 6-50 pg/mL
Total Testosterone 208 250-1100 ng/Ml
Free Testosterone 62 25-155 pg/mL
Results 5/31/2012
Pregnenolone,MS 39 <151 ng/dl
11/7/2012 (Test Cyp Shot)
Testosterone Total 772
Free 250 (range 50-240)
Estradiol 51.4 (0-40)
12/06/2012 (Twice a week)
Testosterone Total 758
Estrodial 41 (0-40)