Hey guys, I’ve been on 100mg enanthate/wk for about 4 months and have been dealing with some anxiety-induced insomnia (also my resting HR sometimes seems significantly too high to sleep) and recently developed sleep apnea symptoms in the past week. My BP is normal and RBC/hematocrit is 5.8 so it’s not “high”. I’m going to experiment with going even lower than 100 even though there may be no point, but I have clomid on hand if I decide to completely stop TRT and start PCT after 2 weeks. I know the “100mg/day for 2 weeks, 50mg/day 2 weeks, 25 for 2 weeks etc” is a common protocol but I’d like to hear if another protocol worked better/faster for you guys. Also if anyone’s dealt with what I have going on, any feedback is appreciated.
It may not be the TRT causing these symptoms of anxiety, it can be as simple as a nutritional insufficiency. You most likely don’t need a PCT for the short time you’ve been on TRT.
Monoamine oxidase A gene
The MAOA gene provides instructions for making an enzyme called monoamine oxidase A. This enzyme is part of a family of enzymes that break down molecules called monoamines through a chemical reaction known as oxidation. Among the monoamines broken down by monoamine oxidase A are certain chemicals that act as neurotransmitters, which transmit signals between nerve cells in the brain. Neurotransmitters are broken down when signaling is no longer needed.
Specifically, monoamine oxidase A is involved in the breakdown of the neurotransmitters serotonin, epinephrine, norepinephrine, and dopamine. Signals transmitted by serotonin regulate mood, emotion, sleep, and appetite. Epinephrine and norepinephrine control the body’s response to stress. Dopamine transmits signals within the brain to produce smooth physical movements.
Monoamine oxidase A also helps break down monoamines found in the diet. It seems to be particularly important in the breakdown of excess tyramine, which is found in cheese and other foods.
Monoamine oxidase A appears to be involved in normal brain development before birth. The enzyme plays a role in the controlled self-destruction of cells (apoptosis), which is an important process in the development of many tissues and organs, including the brain.
Treatment → magnesium, pregnenolone.
What dose of clomid does your doctor prescribe?
I once had T levels go from 290 to 790 ng/dl on clomid.
That’s an interesting take he has on pregnenolone. He can’t be right. 100mg daily for anyone and everyone?