I dont post much but read and learn daily on the forum and respect those on here that have a greater understanding of this topic.
Just thought you might be interested in knowing Poliquin’s take on Tamoxifen. Just finished the first day of his bio sig course here in London and he mentioned that Tamoxifen is the worst drug to use in PCT because it sends IGF levels into the toilet. He said never to use a SERM and in particular Tamoxifen but always use Arimidex. Just wanted to throw the cat among the pidgeons here as i know most of you go with Tamox for PCT. Any thoughts guys?
I am not real up to speed on this yet, I have read some things but far from enough.
theres things published from 1992 that I am reading about this.
My understanding is that the study was done on breast cancer patients,(on label recommendation of the drug)
it is a different dosing protocol and different duration.
it does lower igf-1 how much depends on how much and how long the drug is taken.
also after you stop taking it your levels go back up to the pretreatment levels, this was also in the study.
they tested the levels at 12 weeks and some were tested at 2 years of use @ 20MG a day
we never take it for that long.
and when they stopped they were back at normal igf levels within a couple days.
so heres my thing,oversimplistic and all
lets say a person was in a hormonal state for about 12 weeks that was very highly anabolic.
who cares if you have a minor drop for 4 weeks.
for a month you will have slightly dropping IGF levels, how low they will drop,hard to say but it wont be that much in 4 weeks. I mean honestly it wasnt that much after 12 weeks in these patients.
and when you get off a few days later your back to normal.
normal hormone levels across the board.(thats the goal anyways)
really with everything else going on I really dont see it as that important.
and if in doubt then add some IGF-1 to your pct.problem solved.
but really these tests were done on women and not done on males especially males that have the hormonal profile of an AAS user. so its really not quite accurate to say not to use it in PCT as thats not how it was tested.
EDIT: the levels that were “in the toilet” were I believe results taken after 2 years of use.
4 weeks is not going to send them “in the toilet”
again I could be mistaken I havent read much on it