The weird thing is, regardless of all that is has went on the past few months I don’t consider myself to be depressed, anxious or particularly low energy. I don’t really have “fatigue” per say and usually wake up refreshed. How can this be explained? haha
My guess.
These are not bad enough numbers to give you those symptoms.
I believe in US terms your TT is 457ng/dL most don’t start feeling low T until they go under 300.
17-BETA ESTRADIOL - 19 pg/mL ( < 60 )
What Is the mechanism of action that causes these issues with Cipro? I was always aware of the fact that it could cause your Achilles tendon to snap, but I didn’t understand why. .
Yeah, I’m taking collagen peptides at the minute and hoping for the best with it. I have low E2 myself, so that is definitely a factor in all of this - with you on that one.
The mechanisms are not fully known, but it damages all connective tissue in the body (pretty much). Tendons are just the first thing you notice. The theory is that some people have phase 2 detoxification issues (through MTHFR genes or liver enzyme dis-regulation) and the drug builds up to dangerous levels in the body. Because the drug by it’s very nature, reduces the enzymes responsible for antioxidants (70% in the case of Cipro), and the fluorine (flouride) molecule can arguably became stuck in the cells in the body and can’t be removed.
The only way to remove is through high dosage IV antioxidants (glutathione), but due to genetic polymorphisms I am sensitive to this and can’t go that route.
Cipro ruins your body, it’s hard to recover fully from.
Yeah, doing everything I can do to reduce the level of oxidation in my body and help my body heal. It’s been very hard though, since brain fog is impacting my work badly. It’s been said that “with time” it heals to a large degree, so hoping all my effort is not to waste. Keeping a close eye on my bloods as well.
I don’t think touching my testosterone levels at this time is a good idea, because I’ve heard testosterone by it’s very nature can create an oxidative environment, not to mention trying to “dial in” for months on end while dealing with these symptoms as well. Going to give it 6-12 months and re-visit TRT, I don’t feel like complete death at this time so maybe I can recover at least back to my usual crappy state (with a functional brain though! haha).
I think it’s always been high to be honest (all tests show this - including pre-cipro), hence me feeling like junk a lot of the time! The super strange thing is I never really had fatigue, depression, anxiety, muscle/joint pains, etc. The only issues I really had were difficulty gaining muscle, low libido/ED, and some weight gain. After Cipro, I got all tendon pain, neuropathy, etc.
Thanks for the info on SHBG though, makes complete sense and I will be on the watch for that. I am currently supplementing with Iodine with some good results.
Hi, I am 22 and I’ve been floxed 4 years ago and I am still recovering but I am literally tired of this, it makes my living a misery. I am thinking seriously about TRT. How was your experience/recovery as a floxie while and after being on TRT?
Research intestinal dysbiosis and Fecal Microbiota Transplants (FMT). Work with a Naturopathic doctor and have them order a Genova Comprehensive Digestive Stool Analysis. Your microbiome is likely no good from taking antibiotics; you killed off too many good strains. FMTs can be done at home using stool from a healthy donor via enemas. Treatment (ironically) is a course of antibiotics (Augmentin with Vancomycin is a good combo) to wipe out the colon as much as possible prior to the fecal transplants. 10 FMTs in a period of 10 days is the minimum for optimal clinical outcomes.