PLAZMA Reactive Pump

Plazma™ Reactive Pump is for elite athletes and serious bodybuilders and lifters whose hard-working muscles require advanced nutritional support. The Plazma™ formula produces a high-performance pump making muscles fatigue resistant and stronger during the most brutal workouts and competitions. Plazma™ doses enable you to perform at and beyond your limits while recovering faster, and faster recovery means faster and more significant gains.*


  1. Increases muscle gain by 70% over whey hydrolysate (Demling RH, 2000).*
  2. Doubles fat loss over whey hydrolysate (Demling RH, 2000).*
  3. Enhances nutrient uptake in muscle, directly affecting AMP-activated protein kinase signaling in the cell (Iwasa M, 2020).*
  4. Improves VO2 max performance significantly and reduces exercise-induced muscle soreness (Saunders MJ, 2009).*
  5. Makes intense exercise actually feel easier (Furuyashiki T, 2014).*
  6. Increases levels of powerful metabolic regulator FGF-21, which improves insulin sensitivity in muscle (Fangmann D, 2020).*
  7. Increases VO2 max time to exhaustion by 70% in elite swimmers (Shirak T, 2015).*
  8. Decreases stress hormone levels following exhaustive exercise (Suzuki K, 2014).*
  9. Provides rapid hydration and nutrient loading without increasing gastric emptying time (Takii H, 2004).*
  10. Increases endurance to fatigue by 27% over glucose supplementation and doesn’t spike insulin in comparison (Takii H, 1999).*

You can’t push the body past where it begins to break down without devastating consequences. However, if you preload and pump working muscles full of critical nutrients, you can significantly boost performance while minimizing damage and inflammation. You can train harder and recover faster.

Taking Plazma™ doses — before, during, and after training — keeps muscles pumped full of the key nutrients for maximum performance and enhanced recovery. The term for this muscle-engorging effect is called the “reactive pump.” The reactive pump makes muscles hyper-responsive to nutrient uptake and growth signaling, producing unbreakable performances in the gym and competitions.

Here’s Feedback from Two Fitness Legends: Dave Tate and John Meadows.

“You get leaner almost daily while gaining muscle and strength.”

When Biotest CEO Tim Patterson first asked me about trying Plazma™ dosing, I was extremely skeptical. But I took him at his word, gave it a shot, and was completely blown away by the results. In fact, I contribute much of my recent success to Biotest’s Plazma™ formula. It flat out works. You get leaner almost daily while gaining muscle and strength. It’s nuts.

I feel like the Plazma™ protocol buys me considerable leeway. I can basically screw up my diet everywhere else, and as long as I take this supplement, I’ll meet my body’s needs and grow. That’s a huge plus for me. I have enough to think about, so the last thing I want is to be stressed about what I eat. It’s nice knowing that as long as I have Plazma™ during my workout, I can basically cruise through the rest of the day. So if anything, this workout protocol is a huge stress reliever.

— Dave Tate

“I feel like I’m unbreakable.”

Testing the Plazma™ formula, I did things that I’d never advise anybody to do, like crazy intensity and insane volume. I didn’t cramp up, I didn’t get sore, and I got these mind-blowing pumps.

For the next three weeks, I kept training like this and eating a lot to see how much muscle I could gain. Getting leaner wasn’t even on my mind. So when my body fat dropped from about 9 percent to 5 or 6 percent, it was pretty much by accident.

It was so amazing. All I have to do is follow the Plazma™ protocol and go to the gym and train my ass off, which I love to do. That’s it. And to think, I pretty much got in shape by accident.

— John Meadows


Betaine Anhydrous

Betaine anhydrous increases muscle power, endurance, workout capacity, and muscle mass. It also increases leanness, improves overall body composition, and helps liver function and cell reproduction.* LEARN MORE

Casein Hydrolysate

Casein hydrolysate is a pharmaceutical-grade milk protein that’s quickly and easily absorbed without further digestion. It’s significantly more effective in stimulating muscle protein synthesis than conventional casein or whey.* LEARN MORE

Citrulline Malate

Citrulline malate buffers lactic acid and reduces ammonia build-up, which increases athletic performance and endurance.* LEARN MORE


Electrolytes, consisting of the minerals sodium, potassium, magnesium, and calcium, accelerate rehydration, preventing muscle cramps, poor exercise performance, and premature fatigue.* LEARN MORE

Highly Branched Cyclic Dextrin

Highly branched cyclic dextrin uniquely provides high-performance energy without spiking insulin.* It increases work capacity, decreases stress hormones, increases muscle pumps, and promotes advanced active rehydration.* LEARN MORE


Isomaltulose is a low-glycemic carbohydrate from beet juice that promotes active rehydration and improves fat oxidation, prompting the body to burn fat for energy.* LEARN MORE

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Curious as to why Citrulline Malate is used in this “state of the art/amazing” PLAZMA formula rather than the documented, and researched to be better, L-Citrulline[fermented]?

It appears that the malate version is cheaper and doesn’t provide the user with the full dose of the actually important ingredient, L-Citrulline. Care to comment why this is?

And not trying to dump on PLAZMA, but my pre-workout powder I take has everything in this formula, including the HBCD[the cyclic dextrins], just minus the casein hydrolysate. So, for 39.99 vs. 92.00, I get the same thing just not the protein. I usually just supplement with quality, fermented BCAA powder [price $24.99] which I also mix into my pre-workout drink since from all I’ve read, the KEY amino acid, L-Leucine, which is responsible for signaling anabolism/positive nitrogen synthesis, is in this BCAA mix and in the correct ratio too.
Again, not trying to knock PLAZMA, but I’m curious why the extremely high price? Are we the consumer simply paying a $$$ premium for that one ingredient, the casein hydrolysate?

This is coming from a customer who has a monthly and a bi-weekly subscription to 2 Biotest products which I like extremely well…so for the last time, I’m definitely not against Biotest, but rather curious.

My limited understanding is that casein hydrolysate is extremely expensive.

Casein hydrolysate is also the primary ingredient in Mag-10, and Tim Patterson previously addressed concerns over availability and cost in this thread.

I think citrulline malate is actually the better choice in this scenario because the addition of the malate salt not only increases blood flow like L-Citrulline, but it also provides benefits in terms of energy production and stamina.

Thanks for the explanation…yeah, I figured the casein hydrolysate was the reason for the high $$$ price.

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Oh, sorry I missed this, but something to keep in mind is that Plazma is $69 on subscription too.

Try pricing out bulk casein hydrolsate – it is super expensive!

Yeah, I did look at a few places which carry casein hydrolysate and it is VERY expensive per pound. And yes, I know that it is supposedly MUCH easier to digest and assimilate in your body…but I honestly don’t think, at the crazy expensive cost is it, that is can honestly be THAT much better than a high quality whey protein isolate-made from good cold microfiltration/CFM, etc. Because that type of Whey Isolate is already a bit more on the expensive side yet it supposedly is the purest form, without the lactose, fillers, ash, etc. So, not sure why you’d pay 2-3X more for a protein that, what, digests a bit faster?

What I normally do anyway is take some quality instantized[powdered] BCAA’s immediately before and immediately after my workouts, then have my typical post workout shake with waxy maize starch for carbs and also whey isolate. I really don’t feel that all that extra money to swap my WPI for CH would make a night and day difference. And for that price differential, I’d only swap it if I KNEW I’d experience that type of result. Just my .02

I’ve gone back and forth on my peri-workout nutrition, trying mixes from other companies and even trying Surge Workout Fuel (the only Biotest product I’ve ever returned). I keep coming back to Plazma. I don’t know if that’s psychological or what, but I feel better both during and after my sessions when I’m using it. If I ever try Surge Workout Fuel again I’ll use some whey isolate immediately after to see if that makes any difference for me. But I probably won’t – at ~$3.50 per serving at the subscription price it is easier to just keep on using Plazma.

Was making a Mag-10 preoder today and wanted to order Plazma in the same go… sad to see it’s not in the store. I know it swapped to ‘preorder only’ a few months ago… is it gone for good? (pls say no)