Edit: this topic was made to receive advices on my TRT. I will now use it as a journal to write down my protocol, changes, results, labs and everything in between. I welcome any advice, criticism, discussion.
Hello everyone. I’m going to try to be as exhaustive as I can.
I’m a male, 33 years old. I’ve had all the symptoms of low T since I was 12 years old. Depression, no energy, no strength, no muscle mass, low confidence, you name it. Been through major depressive disorder and tried to off myself twice before 30. Spent the most part of my twenties in therapy, and taking ssris and snris. I’ve been off meds since my 30s.
I’ve been lifting for about 4-5 years seriously but seen slow result, which made me question my hormones. Lo and behold, here are the results:
- T total 5.40 (2.49 - 8.36)
- T free 7.3 (8.3 - 40.1)
- estradiol 27 (9 - 62)
- shbg 42.40 (18.3 - 54.1)
- free t3 2.97 (2 - 4.40)
- free t4 1.51 (0.93 - 1.70)
- TSH 0.5 (0.27 - 4.20)
- IGF1 216 (111 - 244)
I have a lot more values, not sure if they’re useful. This was the blood test before starting TRT.
Now, my doc diagnosed me with hypogonadotropic hypogonadism and started me on TRT.
He prescribed me Androgel, 3 pumps a day. I did that for one week, but had really bad itching, so he switched me to IM test E 250mg / 3 weeks.
I did the first (and so far only) injection on April 4th. Didn’t feel much, but 3-4 days after I became borderline suicidal, depressed and crying, and it lasted for about 5 days. Was back to normal around 10 days after the shot.
I suspected e2 so I went back for another blood work on April 18th (2 weeks precisely after the shot). Here are the results:
- T total 5.51 (2.49 - 8.36)
- T free 7.9 (8.3 - 40.1)
- estradiol 15 (9 - 62) ← that shit halved
- free t3 2.95 (2 - 4.40)
- free t4 1.44 (0.93 - 1.70)
- TSH 0.95 (0.27 - 4.20)
Now I have an issue with several things. First of all, my doc didn’t ask me to check estradiol, I took the liberty to do it. It strikes me as a bit odd to get someone to inject testosterone and not even check for e2. Then, I got back to the doc, told him about the symptoms, not to mention labs being even worse 2 weeks after the shot, but he thinks it’s fine and I should keep the current protocol, which is 250mg every three weeks.
I’m also in Europe (France to be precise), TRT is way less mainstream and docs are less informed (but at least it’s free hey). I’ve read a lot about injecting lower dosage sub-q, like 50mg every 3.5 days or something. But I do not want to act recklessly and inject myself disregarding what my doctor prescribed me, but I’m so far not satisfied with the results whatsoever. I’m due the next 250mg shot tomorrow and I don’t want to have this emotional rollercoaster again.
You guys are most likely more experienced than my doctor, so how should I proceed ? Ask for a second professional opinion ? Keep the current protocol for a while and see if it improves ? Switch to weekly or every half week injections ? I also need to add that I have nurses doing the shots for me, and it will be hard to get them to disregard the standard 250mg IM protocol, so I’ll most likely have to do the shots myself. Which it’s really scaring the shit out of me.