I did 2on 4off a few years ago, and was doing (IIRC) PCT the first two weeks off. PCT each time consisted of a 2 week 40/20 nolva, followed by 2 weeks completely off everything before starting up again. Was using tren/test/mast blend (cut mix) and saw good results - would have been much better if I tightened up my diet, but I wasn't trying to get ripped up or anything. Also, I don't ever plan on using tren again. The stuff is awesome, but between the cardio hit and the other sides I'll go with other stuff instead.
Anyway. My 2 weeks on consisted of 1ml injections ED of the blend (150mg total per day, so 1050mg per week), ending on day 15. Took 1mg arimidex ED with it, but should have taken caber or something similar rather than what I used (Vit E, SamE, and P5P) as well.
PCT was first two weeks after injections ended, 40/20 nolvadex followed by 2 weeks completely off. Last week before starting back up was a grinder in the gym. If I was going to do it again, I would probably do 2/2 or 2/3 because of that. Also, about a month or two after the last short cycle, I felt like shit. Tired all the time, started trying to talk myself out of going to the gym, that type of shit. Did a 4 week 40/40/20/20 nolva PCt again, and that put me straight. So based on that, my recommendation to you would be when you go for that 6 weeks off, do the full 4 week PCT. Should work better than what i did. And it's up to you, but I think 2on/3off with that 2 week PCT would work really well for you. But remember to keep your in-cycle dosing high (a gram or so per week). Get in, get work done, get out and recover.