No, I have not had any feelings so far over almost 3 months on Parlodel in which I feel run over or drained. I would be interested to know how (other then maybe an acute lowering of pulsitile GH levels) as Bromocryptine at the right dose and frequency is also used to treat acromegaly or anterior pituitary adenomas which cause excessive GH release. At the dose I am on I was told I am way too low to experience such hormonal effects.
Prolactin which is produced by lactotrophs in the posterior pituitary gland is suppressed by dopamine release. Bromo is known to effect the substantia nigra area of the brain which produces and releases dopamine. Dopamine was first titled (PIH) prolactin-inhibiting-hormone prior to its more contemporary and well known functions in the reward-pleasure system.
High levels of serum prolactin (above 20ng/dl) causes mild suppression of the endogenous production of T. Enough that it can lead to sub-clinical or even clinical hypogonadism in men. It takes at least 3 months of continuous use of Bromo to allow not only suppressed serum prolactin levels but also elevations in free and bioavailable T. This allows insights to both the upstream targets and the down stream targets of the hormonal production and target tissue responses, better allowing a physician to find the point at which T is being inhibited from being where it should be in healthy, middle aged guys like us.
Thats my understanding of the goods.