One All-Out Cycle vs Infrequent Mild Cycles for Achieving Max Genetic Potential

Guys, in your opinion what is the best strategy for guys who want to achieve their maximum genetic potential (or staying slightly over it) and maintaining the results as long as possible?
Some say that an one epic cycle (and then staying off lifelong) yields the best results in terms of full muscle maturation, but on the other hand running mild cycles (like Test only) every now and then seems less scary for people who don’t want to take too many health risks and don’t want to get super huge.
Also what’s the best option for long term health, other than results?