New to this site, so bare with me. I’m 28 yrs old, and started TRT approx 8 months ago from a specialist. Went into the clinic as a general check up, as I’ve been having symptoms of low test. They did a full blood test, and came back with this back September 2018.
Everything was up to par;
DHEA: 15.8 umol/l
PSA: 0.7 ug/l
FERRITIN: 228 ug/l
HOMOCYSTEINE: 7.2 umol/l
VITAMIN B12: 384 pool/l
VITMAN A: 1.8 umol/l
FREE T3: 4.9 pmol/l
And these were my original Test and Estrogen:
FREE TEST: 275 pmol/l
Estradiol: 205 pmol/l (55.84 pg/ml)
As you can see, my E2 was through the roof, so the Dr. decided to start with arimidex, and see if we an lower it, in turn will boost my test. We started on 1mg of Arimidex per week.
Checked blood levels again in 8 weeks, and they were worse:
FREE TEST: 255.9 pmol/l
Estradiol: 195 pmol/l (53 pg/ml)
So E2 barely went down with 1 mg arimidex per week, and my test is dropping. So the Dr. decided to go on the TRT route, and start with a small dose of 50 mg of Test E per week, just to boost my test a little, without trying to chase the estrogen. Start HCG injections Sub Q at 250iu twice a week because I want to have kids in the near future. He also tripled my Arimdex dose to 3 times a week to lower my E2.
Checked levels again in 8 weeks, with little to no improvement on libido. Definitely got morning wood back, very strong, but almost a roller coaster as it came and went through out those weeks.
FREE TEST: 357 pmol/l
Estradiol: 204 pmol/l (55.57 pg/ml)
Now my test has improved a little, but my estrogen has jumped up again, even on 3 arimidex per week. The estrogen probably went up because I introduced more test in my body, but it’s a small amount, and from what I’m reading, 3mg of arimidex per week should definitely drop my E2 levels.
Now the Dr. decided to try another AI called Letrozole at 1mg EOD. Thinking maybe I wasn’t fully responding to Arimdex.
Went for checkup again in 8 weeks, now with more diminishing libido, and erectile function not up to par. (Half hard, troubles keeping a full erection during sex)
FREE TEST: 610.6 pmol/l
Estradiol: 180 mmol/l ( 49.03 pg/ml)
So now my test is higher and up to standards, I’m still struggling with getting my estrogen into “normal” levels. And my symptoms have been getting worse. Definitely lower libido, the morning woods have disappeared, and incident of ED. So the Dr. again presisited until we get that estrogen down, it still could cause these symptoms. So he added arimdex back in at 1mg twice per week, ontop of the letrozole at 1mg EOD.
Here is my most recent results:
FREE TEST: 622 pmol/l
ESTRADIOL: 158 mmol/l (43.04 pg/ml)
At this point, I’m ready to give up and stop all meds and treatment. Even with the E2 declining slowly in the right direction, I feel like my symptoms are just getting worse and worse. I don’t remember the last time I had the urge to masturbate. Tried to have sex with the girlfriend multiple times, with total ED. Which in turn, is giving me anxiety and depression because I can’t rise to the occasion for my girlfriend. I’m confused on why this is happening, the theory behind lowing my E2 should help, but even with all these AI’s, my symptoms are worse than I started. Before any treatment, I never had ED before. Maybe slight decrease in libido, and maybe not up to full mask every time we have sex. So I’m questioning if I should continue treatment, in which the Dr. insisted taking the letrozole every day at 1 mg, and 1 mg Arimdex twice a week. Or I completely stop, hoping my horomones will find a balance to even go back to what it was before. Any thoughts or experiences on this will help, whether I stick it out and keep lowering my Estradiol to optimum (Dr wants around 75 mmol/l, 20 pg/ml), or stop all treatment because the symptoms are worse.