Long story short I have been on Clomid (12.5mg ED) for awhile now after a long battle with Low T. I am 29 years old, 200lbs. Here are my numbers on Clomid currently:
Doc is adding adex (1mg per week, .5 Monday, .5 Friday) to see if any numbers improve.
Can Clomid affect TSH? I’ve had lots of bloodwork and don’t ever remember it being that high. Doc ordered more thyroid bloodwork for more details.
Clomid seems to be working well so we will see what changes on the Adex. Another option he gave was 1500iu HCG 2x per week along with the Adex. Anybody think this would be better than Clomid+Adex?
Good plan as you are in the danger zone as far as estrogen issues. E2 should be closer to 22
Yes it sure can, please see the attached link. Glad to hear your doctor is looking further into it.
The second option is crazy. 250IU of HCG every other day closely mimics the bodies natural LH production as far as quantity. 3000IU weekly would be six times the amount and you would likely find desensitization in the testes after 30-90 days (I can link the study if you like).
Given the side effect profile of clomid I would say so, but each person is different. The decision is personal, for me it was testosterone was the option as if I had to take shots it may as well be test. But for me fertility was not a concern.
It is an LH analogue, it would shut down the natural production of LH and FSH. However, even though it is not and FSH analogue, you would not be sterile.
LH/FSH could be better, more clomid possible.
E2=31 is not too high, you can try 1/4mg anastrozole twice a week
Lower E2 in itself might improve LH/FSH a bit.
hCG has no advantage over clomid induced LH. However, hCG is a natural human hormone.
Do you feel OK with clomid? Mood problems?
TSH:
Have you been getting iodine from iodized salt?
Feeling colder lately?
Outer eyebrows sparse?
See “oral body temperatures” below.
Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.
KSman is simply a regular member on this site. Nothing more other than highly active.
I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab number and ranges.
The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.
1/4 tab Anastrozle twice per week is what I’m going to try. We will see what that does to the Free T and SHGB numbers. My TSH is never that night so we are going to check it again in six weeks along with the other normal stuff. I do use iodized salt. I don’t have any of the symptoms you mentioned.
I feel pretty good overall. Will report back when I get bloods again in 6 weeks.
@KSman got it. My total t is high 600’s even with LH at 3.3. so HCG should technically work well if my dose turns out to be something that corresponds to LH > 3.3. free t and shbg is killing me right now.
Alright, my doc will allow me to try TRT (Cyp, HCG, AI). 100mg per week 1x per week. My question is, what dose/timing of HCG is the most up-to-date protocol when doing a 1x per week injection of test? I’ve seen every other day, E3D, and also just both days before your next injection to try and prevent levels from dropping off before the next shot. Suggestions? Along with that, what dose/timing for Arimidex as well?
One inject per week with your SHBG level doesn’t make sense, inject T twice weekly using insulin syringes in shoulders or thighs and take AI at injection time. Inject HCG 2-3 times weekly.