On an Empty Stomach?

Some vitamints, supplements, medicines what have you have the instructions eat on an empty stomach. What exactly does that entail? Obviously not have eaten anything within at least, what 30 minutes or so? But can I eat directly after? Is there a window of not eating around taking the above mentioned item?

Also on a side note, what happened to the tip of the day? It has been gone forever, I miss that.

The general rule is 2 hours after eating, and then wait 30 minutes to eat afterwards.

Obviously it depends on how much you eat at a time, what kind of food, your individual metabolism, etc. But it gives you a starting point.