T Nation

Numbers Look Great, But I Ain't Feeling It

Results are in guys, help a brotha out.
22 years old
195 15%bf
Had a thorough blood work here.

40mgs Test Cyp 2x week, 50mg dhea and preg daily, no ai, no hcg

Okay Gents, so adrenal isn’t optimal but it’s still in range, thyroid as well. I’ve ruled out sleep apnea so I can’t really figure out my problems. Iron is off though, although doc said it’s nothing to worry about. Still I donated blood, but feel no different.

dry mouth, tongue
light headed, if standing up too fast
Red arms, face, upper chest
joint pain
throat pain
vision problems
MY bp has gone up quite a bit from 120/80 to 150-160/80 which is really bothering me.

Mentally I feel great, physically somethings off though…
I’m pretty lost about what to do…

CBC With Differential/Platelet
WBC 4.8 3.4-10.8 x10E3/uL SO
RBC 5.12 4.14-5.80 x10E6/uL SO
Hemoglobin 15.7 12.6-17.7 g/dL SO
Hematocrit 46.6 37.5-51.0 % SO
MCV 91 79-97 fL SO
MCH 30.7 26.6-33.0 pg SO
MCHC 33.7 31.5-35.7 g/dL SO
RDW 13.0 12.3-15.4 % SO
Platelets 259 155-379 x10E3/uL SO
Neutrophils 58 40-74 % SO
Lymphs 34 14-46 % SO
Monocytes 6 4-12 % SO
Eos 2 0-5 % SO
Basos 0 0-3 % SO
Neutrophils (Absolute) 2.8 1.4-7.0 x10E3/uL SO
Lymphs (Absolute) 1.7 0.7-3.1 x10E3/uL SO
Monocytes(Absolute) 0.3 0.1-0.9 x10E3/uL SO
Eos (Absolute) 0.1 0.0-0.4 x10E3/uL SO
Baso (Absolute) 0.0 0.0-0.2 x10E3/uL SO
Immature Granulocytes 0 0-2 % SO
Immature Grans (Abs) 0.0 0.0-0.1 x10E3/uL SO

Comp. Metabolic Panel (14)
Glucose, Serum 80 65-99 mg/dL SO
BUN 13 6-20 mg/dL SO
Creatinine, Serum 0.95 0.76-1.27 mg/dL SO
eGFR If NonAfricn Am 113 >59 mL/min/1.73 SO
eGFR If Africn Am 131 >59 mL/min/1.73 SO
BUN/Creatinine Ratio 14 8-19 SO
Sodium, Serum 138 134-144 mmol/L SO
Potassium, Serum 4.2 3.5-5.2 mmol/L SO
Chloride, Serum 99 97-108 mmol/L SO
Carbon Dioxide, Total 24 19-28 mmol/L SO
Calcium, Serum 9.7 8.7-10.2 mg/dL SO
Protein, Total, Serum 6.6 6.0-8.5 g/dL SO
Albumin, Serum 4.4 3.5-5.5 g/dL SO
Globulin, Total 2.2 1.5-4.5 g/dL SO
A/G Ratio 2.0 1.1-2.5 SO
Bilirubin, Total 0.8 0.0-1.2 mg/dL SO
Alkaline Phosphatase, S 57 39-117 IU/L SO
AST (SGOT) 21 0-40 IU/L SO
ALT (SGPT) 23 0-44 IU/L SO

Urinalysis, Routine
Specific Gravity 1.007 1.005-1.030 SO
pH 6.5 5.0-7.5 SO
Urine-Color Yellow Yellow SO
Appearance Clear Clear SO
WBC Esterase Negative Negative SO
Protein Negative Negative/Trace SO
Glucose Negative Negative SO
Ketones Negative Negative SO
1 of 3
Occult Blood Negative Negative SO
Bilirubin Negative Negative SO
Urobilinogen,Semi-Qn 0.2 0.0-1.9 mg/dL SO
Nitrite, Urine Negative Negative SO
Microscopic Examination Comment SO
Microscopic follows if indicated.

Lipid Panel
Cholesterol, Total 119 100-189 mg/dL SO
Triglycerides 63 0-114 mg/dL SO
HDL Cholesterol 41 >39 mg/dL SO
According to ATP-III Guidelines, HDL-C >59 mg/dL is considered a
negative risk factor for CHD.
VLDL Cholesterol Cal 13 5-40 mg/dL SO
LDL Cholesterol Calc 65 0-119 mg/dL SO

Iron and TIBC
Iron Bind.Cap.(TIBC) 341 250-450 ug/dL SO
UIBC 109 LOW 150-375 ug/dL SO
Iron, Serum 232 HIGH 40-155 ug/dL SO
Iron Saturation 68 HIGH 15-55 % SO

Vitamin B12 and Folate
Vitamin B12 936 211-946 pg/mL SO
Folate (Folic Acid), Serum 18.5 >3.0 ng/mL SO
A serum folate concentration of less than 3.1 ng/mL is
considered to represent clinical deficiency.

Testosterone,Free and Total
Testosterone, Serum 772 348-1197 ng/dL SO
Free Testosterone(Direct) 15.6 9.3-26.5 pg/mL BN

Hemoglobin A1c
Hemoglobin A1c 5.0 4.8-5.6 % SO
Increased risk for diabetes: 5.7 - 6.4
Diabetes: >6.4
Glycemic control for adults with diabetes: <7.0

TSH 2.400 0.450-4.500 uIU/mL SO
Thyroxine (T4) Free, Direct, S
T4,Free(Direct) 1.44 0.82-1.77 ng/dL SO
Triiodothyronine,Free,Serum 3.5 2.0-4.4 pg/mL SO

DHEA-Sulfate 405.4 164.3-530.5 ug/dL SO

Luteinizing Hormone(LH), S
LH <0.2 LOW 1.7-8.6 mIU/mL SO

FSH, Serum
FSH <0.2 LOW 1.5-12.4 mIU/mL SO

Prolactin 11.4 4.0-15.2 ng/mL SO

Prostate-Specific Ag, Serum
Prostate Specific Ag, Serum 0.3 0.0-4.0 ng/mL SO

C-Reactive Protein, Cardiac
C-Reactive Protein, Cardiac 0.71 0.00-3.00 mg/L SO
Relative Risk for Future Cardiovascular Event
Low <1.00
Average 1.00 - 3.00
High >3.00

Estradiol, Sensitive
Estradiol, Sensitive 19 3-70 pg/mL BN

Estradiol 55.2 HIGH 7.6-42.6 pg/mL SO
This one throws me off as with the standard lab here my estrogens high, while the sensitive panel looks great.

GGT 11 0-65 IU/L SO

Magnesium, Serum
Magnesium, Serum 1.8 1.6-2.6 mg/dL SO

Insulin 4.0 2.6-24.9 uIU/mL SO

Ferritin, Serum
Ferritin, Serum 64 30-400 ng/mL SO

Sex Horm Binding Glob, Serum
Sex Horm Binding Glob, Serum 34.5 16.5-55.9 nmol/L SO

Cortisol - AM
Cortisol - AM 18.1 6.2-19.4 ug/dL SO

ACTH, Plasma 39.9 7.2-63.3 pg/mL SO

Reverse T3, Serum 18.5 9.2-24.1 ng/dL

No thyroid meds.

RT3 Ratio: 18.9

4X Cortisol Test
DHEAS (saliva) 22.0 ng/mL 2-23 (Age Dependent)
Cortisol (saliva) 5.3 ng/mL 3.7-9.5 (morning)
Cortisol (saliva) 4.4 H ng/mL 1.2-3.0 (noon)
Cortisol (saliva) 1.3 ng/mL 0.6-1.9 (evening)
Cortisol (saliva) 0.5 ng/mL 0.4-1.0 (night)

So cortisol seems low. DHEA was also previously low before supplementing, leading me to think my low energy is adrenal related as my labs look pretty good.

Sorry to resurrect this old thread but I believe this shows the importance of estradiol sensitive LC/MS vs the standard estradiol test. If he went based off his standard test of E2 = 55 then he would be adding Anastrozole to his protocol because the standard estradiol test is not as accurate as the sensitive test. Personally I felt better when my standard estradiol test showed E2=31 than I do now at E2=21.

Taken from discounted labs…

”The commonly used estradiol test may overestimate estradiol. That test uses immunoassay technology that cannot differentiate C-Reactive Protein (involved in inflammation) from estradiol, so it reads the combination of the two as estradiol. This sensitive estradiol test is based on liquid chromatography/mass spectrometry (LC/MS), an assay technology that does not have that limitation.

Adult Men. The use of a sensitive, LC/MS assay for serum E2 measurement in males is preferred over direct immunoassays because of its greater sensitivity and lesser interference by other steroids"

Thoughts guys? Is E2=22 from a sensitive LC/MS test what we are looking for?


I really have avoided getting into that when its all a different deck of cards at each testing company. {sigh}