39yrs old, 260lbs, 12 years lifting
Running 600mg test cyp and 400mg tren e, weekly
Iinitial labs had estradiol at 127.4 pg/ml)
Began aromasin at 12.5mg 3x wk
Two weeks later labs failed to detect estradiol (<2.5 pg/ml). In other words, crashed. Empirical symptoms consistent with low estrogen.
This is not the first time I’ve crashed my estrogen to undetectable levels and frankly, it’s getting annoying. Especially when prepping for a competition. I’ve crashed 3 times before on arimidex. Each time I’ve returned to using an AI I have lowered the dose. After the last crash I did a little more research, spoke with some knowledgeable people and decided to try aromasin. Same results. I have never taken an AI proactively, it is only after high estrogen symptoms are confirmed by labs. I believe I am an over-responder to AI’s.
I’m up to date on the current body of advice in the wake of estrogen crash - wait it out, stop taking the AI, do fewer injections but higher amounts, do IM injections, use dhea, hcg, pregnenolone, etc…
For those of us who have crashed E2 and felt its crippling effects, relief cannot come soon enough. And while the advice may be sound, it also seems a little anemic for what in my mind has been the most profound negative side effect from AAS use and management. I suspect that is because there are relatively few of us that have really been in the shit with regard to crashed estrogen.
This is not a thread for the casual AAS user or the guys that have no trouble with managing estrogen or whom have never crashed it. This is for those of us who’s estrogen is like two fat kids on a teeter totter with a fulcrum as fine as a razor.
With all the use of AAS and ancillaries, why haven’t we considered exogenous management of estrogen/estradiol? Two drugs, an AI and exogenous estradiol could solve this problem, couldn’t it? The AI (like aromasin) used in a high enough dose to eliminate aromatization (and in so doing wipe out all endogenous estrogen) paired with low dose exogenous estradiol (eg Estrace) would allow us to “dial in” estradiol, would it not? Am I missing something here?
If that is too great a leap, what about simply using exogenous estradiol as a first response to an estrogen crash? Perhaps a short course of low dose?
On the other we have recovery from a crash. Would clomid help? We all know that clomid has two isomers, zuclomifene which is estrogenic and enclomifene which is antiestrogneic. Depending on the tissue and the isomer, clomid can produce positive or negative effects (greatly simplified). Could it help restore the most commonly associated negative side effects of an estrogen crash? Namely libido, energy, and sense of well being? Could it expedite recovery?
I know what many of you are thinking. Wait it out. Wait it out. I’ve done that, I will do that again if necessary, but I think its time we advanced the cause for those of us for whom this is a major issue.