Not Feeling Well. Please Help with E2 Levels

When you lower T dose, you need to also use less anastrozole.
Based on E2=10, you need to reduce anastrozole by 50%. If you get a liquid product, google liquid anastrozole, reduce dose by a factor of 10/22. The goal is E2=22pg/ml.

When on TRT, both LH and FSH should -->zero. When LH–>zero and FSH does not, we are concerned that there might be a FSH secreting testicular cancer and in this case it would be minor in some regards, but you must get testes examined. hCG may increase testicular activity and more FSH could result, but LH will still be ~zero.

What meds are you taking?
Could be why potassium is what it is.

You should be testing TT and FT!

Yes, you might need more T. And if you increase T by 20%, increase calculated anastrozole by 20 percent as well. Take anastrozole at time of injections.

Are you diabetic?

Did you post the same lab set twice instead of most current? If so, comments re E2 and anastrozole dose may be at risk.

Please see below re thyroid function, iodine and oral body temperatures. This can be very important.


Please read the stickies found here: About the T Replacement Category - #2 by KSman

  • advice for new guys - need more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Evaluate your overall thyroid function by checking oral body temperatures as per the thyroid basics sticky. Thyroid hormone fT3 is what gets the job done and it regulates mitochondrial activity, the source of ATP which is the universal currency of cellular energy. This is part of the body’s temperature control loop. This can get messed up if you are iodine deficient. In many countries, you need to be using iodized salt. Other countries add iodine to dairy or bread.

KSman is simply a regular member on this site. Nothing more other than highly active.

I can be a bit abrupt in my replies and recommendations. I have a lot of ground to cover as this forum has become much more active in the last two years. I can’t follow threads that go deep over time. You need to respond to all of my points and requests as soon as possible before you fall off of my radar. The worse problems are guys who ignore issues re Thyroid, body temperatures, history of iodized salt. Please do not piss people off saying that lab results are normal, we need lab numbers and ranges.

The value that you get out of this process and forum depends on your effort and performance. The bulk of your learning is reading/studying the suggested stickies.