Not bill obviously.
However, this is somewhat addressed to Jason.
Cocaine is far from just a NE reuptake inhibitor, it has
multiple effects on the dopamine and serotonergic systems as well.
In fact, many stimulants are confused as primarily dopaminergic when often they act on several systems significantly. For example amphetamine or methylphenidate (cocaine’s benign cousin)
are known in ADD to alter the dopamine and serotonin balance which is believed to result in their paradoxical calming effects in children with hyperkinesis. Note- the dopamine effect are primarily responsible for the rewarding properties of all drugs and life for that matter…
Stimulants are not good long term options—IMO.
Don’t get me wrong, these drugs have their uses.
However, long term use of these boys lead to significant depletions of monoamines and vasopressin levels.
They also increase cortisol and CRF.
(not a good thing)
CRF antagonists are currently being researched as next generation
Plus, sadly tolerance seems to build with chronic use.
You don’t get that big bang for your buck any more
due to receptor changes or
a more efficent removal from the blood.
Modafinil is a much safer stimulant though not anywhere as fun.
It can be found here in the states as Provigil.
It is similar (feeling) subjectively to caffeine only there are no jitters
or anxiety issues.
very clean but
not as powerful as the classic
upper class drugs.
Please note cocaine is not nearly as convient of
a social drug as amphetamine either.
The high is short and steep.
Amphetamine on the other hand has a much longer halflife which theoriticallly could be extended by
a mild alkanizing of the blood.
(maybe glutamine or sodium bicarbonate).
Some studies have shown
a increase in half life by 7 hrs using this method.
Some people like to mix low dose Ghb with
This method is referred to as “maxing”.
Believe me when i tell you this works wonders.