T Nation

Nolvadex half-life?

Does anybody know the half-life of Nolvadex in the body? If I’m taking 20mg daily, should I split it into two doses, or just take all at once?

The halflife has been reported variously as 7 or 10 days. So there is certainly no point in taking more than once per day.

In women, if no loading dose is used, it takes SIXTEEN WEEKS to reach steady state levels. So I would recommend a loading dose of 8 times
the daily dose, taken in 8 separate meals (which might extend over more than 1 day, being so many doses.)