That is a low dose. You have to remember that side effects from clinical studies come from females, frequently overweight, probably with decades of oral birth control, with estrogen positive cancers who may also be subject to chemotherapy, radiation, surgeries and associated drugs, aromatase inhibitors. If you have any issues, you stop. Your routine labs should screen for some liver issues via AST/ALT.
If a patient has a heart attack during a clinical trial, they have to list heart attack, if the break a leg skiing, they list bone fracture, if they have a divorce and she gets depressed, they have to list depression. The try to screen out candidates with health issues, but shit still happens.