T Nation

NO Xplode Questions

I have a couple of questions about No Xplode. First how long do you have to take NO Xplode before you can start feeling the effects? I’ve been taking 2 scoops for 4 days now and it makes me feel drowsy. Second your suppose to take NO Xplode 30-45 min before my workout on a empty stomach. I usually eat lunch 30-45 min before my workout and that worked fine. Whats considered a empty stomach? and is it possible to eat food and take NO Xplode without losing the effects?

[quote]Bho75 wrote:
I have a couple of questions about No Xplode. First how long do you have to take NO Xplode before you can start feeling the effects? I’ve been taking 2 scoops for 4 days now and it makes me feel drowsy. Second your suppose to take NO Xplode 30-45 min before my workout on a empty stomach. I usually eat lunch 30-45 min before my workout and that worked fine. Whats considered a empty stomach? and is it possible to eat food and take NO Xplode without losing the effects?[/quote]

There isn’t a whole bunch of support for NOX supps here. Do a search and see what I mean. Personally, I tried it and didn’t care for it. It made me jittery and didn’t make my workouts any more intense.

All i get out of NO Xplode is a huge headache. Im going to continue using it for another week, if it doesn’t start working im gonna toss it

Mate,

Do a search for NO supplements and you could also try NO Xplode search on T-Nation. You will likely find little support for it.

I think David Barr may have written an article about it - basically NO is crap and a waste of money.

Better to buy Metabolic Drive for protein and Surge for peri/post-workout.

NO Xplode is good $hit in my book. I use it before every workout and I seem to get better longer lasting pumps. May be placebo but, that means it is still working in tricking my mind and body into believing it is doing something. Stuff sells like crazy at the supplement store I work at too so, it must be doing something for other people too. As far as how to use it goes just read the instructions on the jug and follow it as it directs.

The jitters that the other guy was yacking about comes from the Caffeine in it. Most of the NO powders are loaded with caffeiene and a lot are coupled with NOOTROPICS to help you out in focusing on the task at hand. If you aren’t getting anything outta it then don’t buy it anymore. Simple as that.

Try this:
http://www.T-Nation.com/findArticle.do?article=05-018-feature

You’d probally be better off taking a Spike Shooter with Power Drive a little bit afterward for a boost rather than NO Xplode.

On the same line I used another of my SuperPump250 for todays workout and I swear I had one of the best in weeks. As much as I hate on these supps I def felt a difference in focus.

I would never pay 80$ for a “pump” though.

[quote]bboybean wrote:
On the same line I used another of my SuperPump250 for todays workout and I swear I had one of the best in weeks. As much as I hate on these supps I def felt a difference in focus.

I would never pay 80$ for a “pump” though.

[/quote]

Any chance that you get the same “focus” by taking the same quantitiy of of caffeine on its own?

Set $80 on fire, then drink a bottle of Mountain Dew and eat some Skittles.

gave me energy the first few times…other times it would make me feel sick to my stomach…and on top of all that…it tasted like complete ass. Oh yea…and by the way…it gave me the shits…this product should be called ASS XPLODE…and BSN should stand for bullshit nutrition…I’ve used all of their main products…they don’t work.

And even if trhey did work…they are overpriced and ronnie coleman is over inflated. Tripple H has buttcheeks for pecs…stay away from this shit.

Its working great now. About 15 min after I drink 2 1/2 scoops of NO Xplode all my veins pop out and I feel like the hulk. The only negitive side effect i’ve had is the headaches, but those went away. So far so good and it wasn’t too expensive, I bought 1.81 pounds for 32 dollars.

[quote]Bho75 wrote:
Its working great now. About 15 min after I drink 2 1/2 scoops of NO Xplode all my veins pop out and I feel like the hulk. The only negitive side effect i’ve had is the headaches, but those went away. So far so good and it wasn’t too expensive, I bought 1.81 pounds for 32 dollars. [/quote]

I’ll try one more time:
http://www.T-Nation.com/findArticle.do?article=05-018-feature

STRONG
WORDS
“nice boy, but he doesn’t listen to a word you say” -Foghorn Leghorn

This is probably going to be a complete waste of my time, but too many times have I heard people reference this article as if it is some kind of scripture.

In no way do I mean any disrespect to David Barr. Who I do mean disrespect to are the parrets, who instead of learning and gathering information on their own, rely on the information gathered by others…even if said information isn’t completly acurate.

There are a few things I would like to point out:

  1. The specifics of the “studies” performed are not mentioned, meaning that they could have easily been done without proper variables considered. “…the findings do not yet come from peer reviewed publications”.

  2. The “study” evaluated body composition, muscle strength and endurance for 8 weeks. The result: No difference in body fat. There was however a very large difference in strength (19lbs)…and for some reason muscle endurence isn’t mentioned. Possibly 2 out of 3…not bad!

  3. “…an average of 19lbs onto their bench 1RM, while the placebo group added less than six”.

“Considering the other research which showed no effect on blood flow and no time release effect, the results just don’t fit. Whether it be improper group selection, outliers in the data, or measurement error, the results presented remain questionable”.

So then if this “study” had the potential to posses “error”, than is it not possible that some of those errors may have also been while evaluating the effects on blood flow and time release effect, not to mention body fat?

  1. "The placebo effect is when someone uses an inert substance, which should produce no effect, yet somehow still experiences an effect. This occurs frequently when pharmaceutical companies test a new drug. They give one group the real drug and another group an inert sugar pill. Interestingly, the group receiving the sugar pill often has a series of side effects like dry mouth, headaches, dizziness, adding ten pounds to their bench, etc. - all caused by their own minds!

One famous research analysis calculated the placebo effect to account for 75% of a drug’s effect".

So while one group recieved a placebo and gained 6 lbs on their 1RM, the other group who recieved a “worthless supplement”, in other words a placebo gained 19lbs on their 1RM in the same amount of time. Shouldn’t the results have been the same?

  1. "Arginine is the amino acid known to be the most potent insulin secretagogue, meaning that it causes insulin release from the pancreas.

Arginine -> Insulin -> Nitric Oxide -> Vasodilation -> Nutrient Delivery -> Muscle Growth and Strength".

So while there may be other ways to increase NO, this Consumer Alert in no way provides any compelling, or scientifically accepted information to disprove the effectiveness of the mentioned supplement. And through it’s finding on strength gains only stands to PROVE it’s overall effectivness.

hmmm maybe i should snort it so it goes directly to my brain

From another website I visit:


Nitric Oxide Supplements- Big Claims - Zero Science: NO 2 ways about it.

by Paul Cribb, B.H.Sci HMS

Supplements that reportedly increase nitric oxide levels within the body are currently being marketed as powerful muscle builders. The marketers of these supplements claim they increase nitric oxide levels within muscle tissue and a dramatic increase in muscle size, strength is experienced. Other claims also include an increase in fast-twitch muscle fiber strength, endurance, power output, and load capacity from taking these supplements. These reported benefits are quite specific, so I decided to scan the literature for the scientific evidence that supports these claims.

Nitric Oxide - what is it?

Nitric oxide is a colorless, free radical gas commonly found in tissues of all mammals (it?s also prepared commercially by passing air through an electric arc). Biologically, nitric oxide has been shown to be an important neuro-messenger in a number of vertebrate signal transduction processes. Nitric oxide is used in medical treatment; for example, nitroglycerin ameliorates the pain of angina by supplying nitric oxide to the blood vessels that supply the heart. The popular drug Viagra controls erection by regulating nitric oxide in the penile cartilage chamber.

The Research and the Claims

I don’t know where the marketers obtained their literature on nitric oxide. It looks like they are using the same journals as the companies selling Myostatin inhibitors - Alice in Wonderland. Although nitric oxide acts as a cell-to-cell communicator for certain metabolic functions, muscle growth is not one of them. After a review of the available literature I cannot find any research that remotely indicates increasing nitric oxide levels plays a part in increasing protein synthesis, contractile strength or any other biochemical pathway that may lead to increases in muscle mass.

For a company to claim their supplement increases “fast-twitch” muscle strength, the promoters must have instigated or funded some kind of research that involved biopsy procedures and histochemical analyses to extract, assesses and identify these particular muscle fibers from animals or humans, before and after supplementation. However, I could find no documentation (either on their web sites or via a literature scan) that details these findings, only the marketing claims. As far as I?m aware, there is zero scientific evidence supporting the notion that nitric oxide supplements increase “fast-twitch” muscle strength.

There also appears to be no evidence whatsoever that shows increasing nitric oxide levels enhances endurance, power output, and load capacity.

Arginine alpha-ketogluterate is the “active” ingredient reported by one company that sells this type of supplement. It is claimed that this compound increases and maintains a constantly high level of nitric oxide in muscle. Nitric oxide is synthesized within the body using the amino acid arginine, the energy cyclic substrate NADPH, and oxygen. Nitric oxide diffuses freely across membranes but it is a transient signaling molecule. Nitric oxide is by nature, a highly reactive gas that has an extremely short life - less than a few seconds. While there is a lot of research on the effects of nitric oxide, there is no research that shows supplementation with arginine alpha-ketogluterate increases or sustains nitric oxide levels in any human or animal organs.

Can you imagine, a supplement that “creates dramatic increases in muscle size, strength, endurance, power output, and load capacity”, but not a single study to support these claims. Nothing new here. Unfortunately, this is typical sports nutrition marketing bullshit. It’s sad, misleading, and shows you just what these companies think of the intelligence level of their target market.

When new products burst onto the market, you the consumer can cut through the advertising hype quite easily. Simply ask the supplement company making the claims to “show you the research”. A reference is a start, but the actual research study is particularly what your after. You want to see the study, the protocol, the outcome and the University at which the study was conducted. In the present case, you want to see a study showing were this supplement actually increased nitric oxide above a control group, and you want to see the data that demonstrates an increase in lean muscle mass, significantly more than the group without elevated nitric oxide levels.

The fact is, there is no science supporting any of the claims made for so-called nitric oxide supplements. There is no science showing they have any effect on nitric oxide levels and certainly no science showing in effects on muscle growth or increased performance.

Ask yourself why there is no research to support these companies’ wild claims. The simple answer is that research is expensive, make believe products are not. Research provides evidence, fraudulent supplement marketing only delivers hype. It?s far more financially rewarding to sell hype than to produce effective supplements backed by science.

One promoter of a nitric oxide supplement claims to have “brought creatine supplementation to the market” and that their supplement is “the perfected version of creatine”. I?m not sure which market is being referred to but creatine has been used as a supplement for over 40 years. And in NO way are nitric oxide supplements a “perfected version of creatine”. They are nothing like creatine. While creatine is backed by a wealth of research, nitric oxide supplements do not have a shred of scientific evidence that justifies their effectiveness as a bodybuilding supplements.

Bottom line, money spent on these products is money flushed down the toilet.

Read the Real Science

1. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J 1992 6(12):3051-64.

2. Mayer B; Hemmens B. Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem Sci 1997 22(12):477-81.

3. Janabi N; Chabrier S; Tardieu M. Endogenous nitric oxide activates prostaglandin F2 alpha production in human microglial cells but not in astrocytes: a study of interactions between eicosanoids, nitric oxide, and superoxide anion (O2-) regulatory pathways. J Immunol 1996 1;157(5):2129-35.

4. Esposito C; Cozzolino A; Porta R; Mariniello L; Buommino E; Morelli F; Metafora V; Metafora S. Protein SV-IV promotes nitric oxide production not associated with apoptosis in murine macrophages. Eur J Cell Biol 2002 81(4):185-96.

5. Eckmann L; Laurent F; Langford TD; Hetsko ML; Smith JR; Kagnoff MF; Gillin FD. Nitric oxide production by human intestinal epithelial cells and competition for arginine as potential determinants of host defense against the lumen-dwelling pathogen Giardia lamblia. J Immunol 2000 1;164(3):1478-87.

6. Kelly RA; Smith TW. Nitric oxide and nitrovasodilators: similarities, differences, and interactions. Am J Cardiol 1996 30;77(13):2C-7C.

7. Stryer L. Biochemistry 4th Ed. Freeman & Co. 1997.