EDIT I copied and pasted this question on another forum asking for advice from different people.
T Nation was actually the first website that got me to try body building and weightloss when I was in my teens (early 30s now) with the help of Thibaudeau and Chris Shugart. However I stopped lifting weights and weight loss quite a long time ago due to medical issues (some related to hormonal issues and others neurological)**
What I am about to post is a direct copy from another forum I got great advice from but I felt I would come back to the original forum that inspired me all those years ago and see what has changed in TRT Therapy, anti inflammation peptides and MOST IMPORTANTLY GROWTH HORMONE PEPTIDES, WHICH I NEED SERIOUS ADVICE ON AND AM ONLY GETTING MINIMAL ADVICE REGARDING THEM
Anyways I apologize for the caps lock and asterisks. Those are where I feel most attention needs to be applied in my case.
Anyways, here is my post…
First let me say i am totally ignorant to testosterone, peptides, and steroids in general. So i am asking here at the advice of pms i received after posting on both the TRT and Peptide subreddits because people said you guys would be more knowledgeable. (T Nation, and other body building forums)
I also copy/posted this from reddit to get more advice. I feel like i am being pulled in different directions from people who know the science but arnt my doctors
My research doctor said he hopes to bring my testosterone which is around the 100s to at the very least 700+ on a regular basis. (not sure what he wants my free value to be, but whatever coorelates with that).
Just in case its not elsewhere in this thread i am 5 foot 9, early 30s, and 302 pounds.
I also have high estradiol which is about 66, (quest range is normal below 39) so we are concerned about that. We talked about being put on an Aromitase inhinbitor but I have read bad things online and I’m not sure if I should do it? But obviously something is going on with that high of estradiol. I have had 3 MRIs over last few years and Cat scans and blood work checking pituatary gland and it is normal.
I also have low Vitamin d,25 at 16 (30-100 range), DESPITE, being on prescription strength supplements prescribed for a month. I am scribed 50,000 IU. But for some reason after a month my vitamin D didn’t increase so my doctor is increasing the script dosage. I was on 10,000 iu OTC daily for a year which resulted in the most recent 16 value.
My liver enzyme values AST and ALT are normal despite being fatty liver in the past. Through diet and excercise those level are expected to lower.
Here are some of my other labs that are concerning as to why GH peptides and anti-inflammatory peptides are recommended for me.
FIRST, I would be given glutathione and anti-inflammatory peptides after my first 3 months of testosterone to make sure my cholesterol and triglycerides are reduced to more normal levels and measure the lost of weight. he doesn’t want to do the growth hormone peptides if this doesn’t happen.*
Triglycerides-261 (Some of the peptides specifically target triglycerides and mine seem to be extremely high. What can I do diet wise to reduce triglycerides in a fast and thorough way that is sustainable and keep it off?
NON HDL CHOLESTEROL-175
LDL PARTICLE NUMBER-1732 (HIGH RISK>1409)
LDL SMALL-507 (HIGH >219) LDL MEDIUM-459 (HIGH >301) HDL LARGE-4168 (HIGH < 5353)
LDL PATTERN-B (RISK HIGH =B) LDL PEAK SIZE-213.3 (HIGH <217.4)
APOLOPOPROTEIN B-120 (<90)
LIPOPROTEIN(a)-13 (good range, <75)
HS CRP Cardio IQ- 5.8 (optimal <1)
LP PLA2 ACITIVITY-120 (good range, <123)
The doctors at John’s hopkins don’t know right now why I am unable to build muscle mass or lose weight. I was put on a number of extreme dietary changes. First and foremost my weight loss is obviously most important since i am over 300 pounds at 5 foot 9. They started with 1000 calories a day on a intermittent fasting of 8 hours eating and 16 hours fasting for 3 months. I had some results in the loss of 5 - 10 pounds but I should lose far more than that.
They will be doing a full genetic workup to determine and rule out and genetic problems and pituatary gland issues, that may not have been found in MRIs, CAT or blood work, that prevent me from losing weight. but these results wont be back for some time., which is why i am being treated with peptides now.
The rational regarding the growth hormone peptides is to prevent burning muscle that I do have and so I can increase calories little by little and increase weight lifting so I can create muscle to burn fat. A sort of “aid” if you will.
I am currently being treated with the following…
- i just got my HCG injection that calls for… OLY HCG 10,000 IU PWVL VIAL, MIX WITH 5ML DILUENT, INJECT 0.25CC SUBCUTANEOUDLY 3 TIMES PER WEEK.
MY MAIN ISSUE IS IF THIS IS SAFE AND BENEFICIAL IN SOME WAY REGARDLESS OF PRICE BECAUSE I SAVED UP FOR IT. IT IS EXPENSIVE, HOWEVER, BUT I AM WILLING TO GO THROUGH HOPKINS RESEARCH HOSPITAL TO HELP UNDERSTAND AND TREAT MY INABILITY TO LOSE WEIGHT, AS NOT GAIN MUSCLE FROM HEAVY WEIGHT TRAINING
2.Along with this i will be taking 80mg twice weekly of testosterone (received 160mg two days ago and received an immediate mood boost).
As well as the GLUTATHIONE at some point here I believe.
Now the next step would be to be put on Anti Inflammatory Peptides -a period of 2 weeks or 4 weeks, There are 2 daily injections and a pill you take daily Thymosin Alpha 1, Thymosin Beta 4, and BPC 157.
- The last step would be growth hormone peptides
CJC 1295 is an injection done 3 times a day, 6 days a week. Tesamorelin is a 1 time daily injection 6 days a week.
My doctors want me to be on these peptides first before i try the growth hormone and the Tesamorelin.
So obviously i am new and need guidance. Sorry for long post. But i need guidance and help from others who have been through this
One of my other main issues is that the doctor wants to put me on an AI, arimidex first with testosterone due to high estrogen, then anti inflammatory peptides first, then growth hormone peptides and I believe I put those specific ones in my post. I have been asking around and I am getting two very different opinions, both from doctors before this johns hopkins doc decided to help me and regular body builder/weight loss specialists.
However, several doctors (and bodybuilders/weight loss specialists not associated with the hospital) at are giving me different opinions about Arimidex.
My main doctor wants me on it because of my high estrogen level. My endocrinologist (not associated with johns hopkins) doesnt want me on it because she doesn’t want to mess with my hormones in my early 30s. In other words shes more conservative in that regard.
Some of the non doctors who are helping me lose weight also dont want me to be on arimidex. I looked online and it seems like aromitase inhibitors are a hotly debated topic and I have no idea what to do.
I suppose ill follow my main doctor’s advice and take the arimidex due to my high estrogen, but i just dont understand why people and my endocringologist is so against me from lowering my estrogen if it is high?
Lastly, are there any other peptides (growth hormone once my testosterone is “normal range” or anti inflammatory peptides before being put on GH peptides).
Thanks so much for reading! And thanks for being so kind and accepting me to this community. Have a great day!
I apologize for such a long post but I wanted to be as thorough as possible.
If there are any other specifics needed I wish ask my doctor and provide it.