Apologies for creating a different thread on this but feeling really low and hoping I can get advice for a good path forward here. Hope I’m not making this too annoying for mods.
A couple of overview things:
- Started HCG monotherapy on February 14, 2018
Looked at TRT initially because of a bunch of symptoms, ED, low libido, brain fog, lack of energy. My bloodwork showed very low TT and free T.
Went to an anti-aging clinic (Canadian so no other choice) and started HCG for a few months. Did 250 iu EOD protocol. Things didn’t improve. Had bloodwork done again that showed TT higher but my free T actually went down (only slightly but still…)
My E2 raised quite a bit due to HCG from my baseline (from 84 <162 pmol/L to 155<160 pmol/L).
For detailed before/after bloods my other thread is here: https://forums.t-nation.com/t/28-bloodwork-low-t-looking-at-trt-but-want-more-info/249362/33
- Just started Testosterone Enanthate on June 2nd
Toward the last few months, I actually felt way worse on HCG monotherapy than prior to HCG. I started to feel very depressed, unmotivated etc and still had problems with ED/libido anyway and still feel this way now. My doctor then put me on 100 mg test enanthate per week in addition to HCG 250 iu EOD.
Because my latest bloods showed high estrogen I’ve been breaking up my 100 mg test into EOD shots (roughly 30 mg EOD) to hopefully reduce estrogen. Yesterday I did 40 mg in one go and honestly felt way better today than I have in past (felt some libido return too) but just really want guidance that this gets better. I know it’s only been just over a week injecting actual T so I need to be patient.
For those who were depressed/low libido/basically feeling like hell every day from low free T how long did it take on T to feel better roughly? 6-8 weeks? Should I just go ahead and inject a bit more (to 150 mg per week) if it makes me feel better?
I’ve ruled out thyroid at this point - unsure why I’ve been feeling so terrible but outlining a few possible culprits to get feedback on:
My E2 is too high
Could be that now injecting both 250 iu HCG EOD and 30-35mg of test EOD is putting me too high for E2. Clearly, HCG raises my E2 a lot. Don’t want to stop HCG though as I want to keep fertility + balls. Not sure if an AI will help? Maybe switching to everyday injections for both HCG and T? I’ve read that more frequent injections reduce e2 on TRT.
I have a liver issue
My latest bloods showed two results that are typically indicative of a liver problem
SGPT (ALT) 46 <41 U/L
IGF-1 271 87 - 255 ug/L
I need to give it time and marathon training is depleting me as well
This is probably the most reasonable answer until I collect more bloodwork. I haven’t really had the chance to hit the gym hard (like I’ve been itching to) since starting T injections because training for a marathon is eating up most of my free time (marathon will be done this Saturday). Running this long distance just makes me feel depleted and not great unlike doing heavy squats or deadlifts. Always felt better on every level after lifting heavy even pre TRT.
I have adrenal fatigue/cortisol issues
I did a DUTCH test recently which showed my cortisol/cortisone as being way high. That same test also showed my testosterone as being extremely low. I’ve attached it here:
Thank you for any thoughts and help!