That series sucked and didn't even last long. The original Hulk live action show was a certified hit back in the late 70's early 80's. It is what made Bill Bixby's career. At one time, The Hulk was just as or more well known than Spiderman. the same goes for Wonder Woman.
If they find people who can play the alter egos well enough for people to care who they are, they can make it work.
If you don't care about the guy playing Bruce Banner, they may as well not even try.