Hey Mike, there is a wealth of great information in “stickies” on the front page of the T Replacement forum. 200mg/week is near the absolute ceiling of TRT dosages. Most of us are somewhere closer to 100mg/week. You need to be aware of elevated E2 (Estradiol) as no matter how much exogenous testosterone you inject it will be cancelled out by elevated E2. Read the following article as it explains T to E conversion is a very easy to read format. Most of us take an Aromatase Inhibitor to control our E2 levels. Aromatase is the enzyme that binds to Testosterone and converts it to Estradiol (E2).