Finally have some labs to report:
TT 274 ng/dL Range: 291-739
Free T 7.5 pg/mL : 4.3 - 30.4
LH 2.6 mIU/mL : 1.7 - 8.6
FSH 2.7 mIU/mL : 1.4 - 11.2
E2 15 pg/mL : 10 - 42
T3 2.8 pg/mL : 2.3 - 4.2
T4 1.3 ng/dL : 0.7 - 1.5
TSH 4.06 uIU/mL : 0.45 - 5.10
rT3 41. 8 ng/dL : 9.0 - 27.0
DHEA-SO4 184.0 ug/dL : 58 - 257
Dihydrotestosterone 20.0 ng/dL : 16 - 79
antibodies >900 IU/mL : 0.0 - 9.0
B12 533 pg/mL : 247- 911
Folate >24.0 ng/mL : 5.4 - 24.0
Ferritin 60 ng/mL : 11 - 450
I also had a saliva test to measure Cortisol levels and I was normal for the 6am, 4pm and 10pm samples and depressed for the 11am sample ( result of 4 with a range of 5 - 10 nM).
I’m a 52 year old firefighter of 22 years and have had a shitty quality of life the past couple years. Chronic fatigue, brain fog, shitty memory, difficulty focusing, depression and anxiety that have trended toward apathy, ED, lowered libido, cold intolerance and recent weight gain. Back in 2001 I was diagnosed with E.D.S. - Excessive Daytime Sleepiness, which is a form of narcolepsy. Prior to the E.D.S. diagnosis, a night time sleep study revealed I suffered mild sleep apnea. A tonsillectomy was performed and my sleep apnea went away. Noticing that my sleep quality had improved but that my fatigue was largely present, I had another sleep study (a daytime sleep study) that revealed the E.D.S.
There is no cure, at present, for narcolepsy, and it is treated with stimulant drugs. For about 4 years I took 200mg of the central nervous system stimulant Provigil. As I read the book “Adrenal Fatigue,” I wonder if the Provigil use didn’t start me on the path which saw me develop seasonal allergies (grass, dust, mold) which at times were virtually debilitating with fatigue, as well as see my testosterone levels tank. I went off Provigil when I saw how anxious it had made me and saw my personal life fraying.
I also have Hashimoto’s hypothyroidism. Back in about '95 I developed a goiter and I’ve been on .2mg of Levothyroxine since. I guess I could be considered a ‘downwinder’ in that I live in Washington state and attended college not far from the Hanford Nuclear Reservation. For years I’ve been taking a multi-vitamin that has an iodine supplement in it and switched back to iodized salt after reading the wisdom of KSMan. I just purchased a digital thermometer and will be tracking my body temperature.
As a firefighter I am constantly exposed to bad shit, from diesel exhaust to who knows what that is produced when stuff burns. Even if I have 100% respiratory protection, which I do not, recent studies indicate that any number of compounds, including chemicals used to make stuff fire retardant, can be absorbed through the skin. We’ve had a shocking number of recent cancer diagnoses in the department and many of them are regarded as “presumptive diseases,” meaning that it is presumed that occupational exposures have caused them.
Firefighting is highly hazardous to one’s health, I’ve come to find. Between the hazardous exposures, the mental/emotional stresses, the physical stresses of waking at all hours of the night, the constant ‘on edge’ physiological state and then taking a CNS drug for 4 years and I think I really did a number to myself. (I should say that I’ve been off the Provigil for 3 years now).
What else? Oh, I developed tinnitus about 2 weeks ago. Fuck, I’m falling apart.
My doctor said it might be worth our time to reconsider the treatment for my hypothyroidism before introducing T, but he thinks that dropping the Levothyroxine (which is a T4 therapy, if I have that right) and monkeying with T3 could be a delicate balancing act that could take some time to get right and could move me from being hypo- to hyperthyroidism. He thinks that there is a T element that could help resolve my elevated rT3 situation, and he thinks we would eventually resort to TRT anyway.
KSMan, I’ve laid a lot out there. I hope you can respond because I’m inclined to pull the plug on injections sooner than later and I told my doctor I’d wait to make a decision until I heard your opinion. He’s curious to hear what you have to say, too.
Thanks for your time!