I actually made some great gains back when I trained 3x a week on a similar split. Of course I didn't work anythign twice a week, only once. I did focus on major compound lifts, and made sure my diet was providing sufficient cals and prot. I believe I split it like this:
Mon - CHest/shoulders/tris
Wed - Back / Bis
Fri - Legs
MOn - INc Bench, Flat Flyes/Dec Press (Superset), SHoulder LAterals, DIps
Wed - Deads, BB Rows, Chins, Inc DB Curls
Fri - Squats, Ham Curls, Extensions, Calf Presses on Leg Press
THat was basically it. I wasn't in the best facility, but I covered all my 'areas' and hit them as hard and heavy as I could. AFter that, its all about recovery.