Had another post going while I was making the decision of whether to to go from Clomid/Anastrozole regimen I’ve been on for 8 years (35mg Clomid 3xweek and 0.1mg Anastrozole 1xweek). My SHBG climbed over the years of treatment and below are my recent labs with Defy. It should be noted that I accidentally missed my AI dose the week before these labs, so my E2 value is 2 weeks since my previous 0.1mg dose (coincidentally, I had strong morning wood all week following for the first time in a long time).
I’ve had my initial consult with Defy (Dr. Calkins) and he recommended and prescribed the following protocol:
- 80mg test twice per week
- 500iu HCG twice per week
- 0.1mg Anastrozole twice per week
- 25mg DHEA nightly
I plan on starting as soon as everything arrives, but he did leave me with a few choices and I kind of have decision fatigue at this point.
- Start at 80mg twice per week and lower later I’d we need to OR start at 70mg or 75mg twice per week and go up if we need to
- IM or Sub Q for my TC injections
Since I’m a TRT virgin, and a lot of you are clearly experienced, would love to see what you think of my protocol as well as the options he’s left me with. One of my concerns is driving E2 too low, but he felt that this is going to get my E2 high enough that I’ll need the 2nd weekly 0.1mg dose.
Thanks and ton in advance and just trying not to run into this blinded by the pure excitement of what TRT may do for me over time. I plan on updating this thread with my journey until I get dialed in.