Has anyone tried the liquid multi-vitamin/multi-mineral called “1st Step”?
Apparently we only abosrb 10% of a pill or capsule therefore this liquid multi claims much better absorption. This product was recommend by the website “Regeneration”. This website focuses on recovery.[/quote]
Wow…I see a number of problems with that product’s claims.
First, as a general rule of thumb, it is true that oral bioavailability of a given compound tends to decrease when going from a solution to suspension to capsule to tablet. However, there are many exceptions to the rule. One obviously being a solid dispersion in a capsule (i.e., the nanodispersion used in nearly all of Biotest’s encapsulated products). In many cases, of course, depending on the physiochemical properties of the given compound, being in a solid dispersion yields a higher oral bioavailability than the same compound in solution or suspension.
As for the 10% absorption. That’s a very interesting, albeit incorrect, figure. To say that each and every compound (i.e., each vitamin and mineral) has the same exact oral bioavailability is ridiculous. This is definitely, the worst and most absurd claim made. The only place I think of where they might have derived that ridiculous figure is the idea of the “first-pass effect” in which many texts will refer to a 90% clearance. But to apply this to every vitamin and mineral is nonsensical. If that’s their reasoning, let’s just forget about everything we know and assume every compound in the universe undergoes extensive first-pass metabolism.
It also seems they’re saying they have a solvent which allows every compound to go in to solution and doesn’t alter or interfere with absorption itself and in fact, enhances the absorption of each compound is almost as bad as the above statement.
In short, whether this product works well for people or not, I don’t know, but the claims made are false.