T Nation

MTOR and Leucine


#1

CT - I’ve been reading up on mTOR and its role in protein synthesis. For those of us (me) who cannot use something like micro-PA, it seems simple and effective to supplement leucine after working out to increase PS. Can you suggest a way to use leucine on non-workout days to keep PS elevated?

It seems like leucine spikes PS for about 2-3 hours, so I’m guessing on an off day it might be of value to wait at least 24 hrs (or 36?) after the last lifting session when PS will start to decline before adding leucine with meals.

Does that seem like a decent approach, or should I not get too into the weeds here? Your help is appreciated, thank you.


#2

I would take leucine PRIOR to working out to enhance the mTOR activation from the workout and 30 minutes prior to every meal on your off days.


#3

[quote]Christian Thibaudeau wrote:
I would take leucine PRIOR to working out to enhance the mTOR activation from the workout and 30 minutes prior to every meal on your off days.[/quote]

I will give that a try, thanks again for your help.