The best advice is to see a good doctor or naturopath who knows how to deal with any possible psychological issues (not saying she's crazy, rather the manifestations of what may be bothering her).
It is very difficult to prescribe supplements for an unknown condition. As you describe, there is an obvious stress/fear response going on. The cause of this is likely not simple, nor will the resolution.
To answer your query, rhodiola has been shown to work in similar situations and I myself have used the Biotest one with some success in a similar situation. Something like ZMA or Elitepro Minerals would help with her sleep in general. Another more accessible method to help with the body's general stress response is chamomile tea.
I would focus on a healthy diet and digestive enzymes, probiotics, and fish oil before other supps that attempt to deal with the adrenals or other systems. Also vitamin D at 5000IU/d and B12 at 3 times 1000mcg sublingual methylcobalamin along with a quality multivitamin/multimineral formula is a good idea. Fish oil at 2-3g/d EPA/DHA (6-10 normal pills, 3-4 Flameout) and probiotics at 18-24 billion CFU of a multi strain mix before each meal.
Perhaps the best thing you can do encourage her to talk and just let her work it out. Listen, but don't try to solve her problems. Basically passive support. If you are able, go for a walk with her in the evening. The fresh air and exercise along with your presence will help more than you think. Also, when relating your own day to day travails, try to put things in as positive a light as possible - not saying shit rainbows, just be philosophical rather than negative if needed.