Considering a “regular” trt dose would only get me to about 300ng/DL accompanied by me feeling like shit I feel inclined to say 100mg/wk isn’t the be all end all TRT dose. It’s all about the patients therapeutic needs, not a number of total MG’s/wk (although there’s certainly a cut-off point) but the cutoff is nowhere near 100mg
This is a myth, while masteron is used primarily as a cosmetic drug, it’s addition of a methyl group in its carbon 2 position protects it from being broken down in muscle tissue by the 3-HSD enzyme, therefore it actually does have anabolic activity. Given the cost of the drug and it’s relatively weaker anabolic effect compared to testosterone it makes it a poor choice for gaining mass (but then again primo is a poor choice for “bulking” too, yet people occasionally use it for that purpose)
Masteron (drostanolone) like most dihydrotestosterone derived compounds has a high binding affinity to SHBG. SHBG is a transport proteinzez, testosterone, estriadol and dihydrotestosterone is bound to shbg, albumin and a teeny tiny, teensy, teensy tiny, tiny tiny tiny bit is bound to CBG (corticosteroid binding globulin), now if you’re familiar with the concept of what SHBG is, CBG is just like that, as in it’s a transport protein for glucocorticoids and progesterone/progestins. ANNYHOW, SHBG does tend to fluctuate but excess androgens will drive SHBG down (how much depends on the androgens binding affinity to SHBG), I believe mast stops estrogen from interacting at tissues (like breast tissue) that are sensitive to the effects of estrogen, similarly to SERMS (however the mechanism is a bit different, I can’t exactly remember what it was or if an exact mechanism as to why was ever determined).
Op’s bloodwork will change depending on how comprehensive the bloods are and the method of testing. Depending on the way they test his testosterone concentration, drostanolone itself could be picked up as excess free testosterone, giving a massive number for free T, his SHBG will be lower, his cholesterol will probably be a bit skewed, HCT/RBC might climb a bit, depending on his reaction to the compound an adverse affect on glucose tolerance/ insulin sensitivity might be seen, however that’s very individual and compound dependent. If he’s dead set on using it long term (which some do), a far lower dose would need to be implimented if he is focused on longevity, while some do run like 200mg test and 300mg mast long term… that’s 500mgs of gear/wk!