That depends on how your pituitary responds and what LH/FSH is produced and how your testes respond to that. If LH is excessive, T–>E2 inside the testes can become high and anastrozole cannot manage that inside the testes and serum E2 can become high.
If SERM leads to the same T levels you had before, I do not see how this is a change and polycythemia expected to be the same.
Please read the stickies found here: About the T Replacement Category - #2 by KSman
- advice for new guys
- things that damage your hormones
- protocol for injections
- finding a TRT doc
- HPTA restart
PMs have been gone for years.