T Nation

Low Oestradiol Results - Advice Needed


Hi guys

Just had my Oestradiol back at

46pmol/L (range 99-192)

Testosterone is 13.3 nmol

I am 30 years old ex propecia users of 5 years

Life changing symptons ED, Chronic Fatigue, Bed Bound, Depression

Thanks in advance


We always need lab ranges with lab results because we do not memorize for all different units and ranges vary by labs too.

E2 is low because FT is low.

Please read these stickies found here: About the T Replacement Category

  • advice for new guys - please provide more info about you
  • things that damage your hormones
  • protocol for injections
  • finding a TRT doc

Propecia may have wrecked your hormones.

Please post other lab work that you have.

Fatigue: Please post your oral body temperatures when you wake up and also mid-afternoon. If low, thyroid function is low.

Are your outer eyebrows sparse?
Do you get cold easily?
Do you use iodized salt and/or vitamins that list iodine+selenium?
How much has stress been a factor in your life?

What is the time line of your issues?


Labs I have had done as follows

Total Protein 71 ( 60-80g/l)
Albumin 48 (35-50g/l)
Total Bilrubin 10 (0-21umol/l)
AST 20 (0-37IU/L)
ALT 28 (10-41IU/L)
Prolactin 190 (86-324mu/L)
Oestradiol 46 LOW (99-192pmol/L)
Testosterone 13.3 (9.9-27.8pmol/L)
VitaminB12 424 (180-2000ng/L)
Serum Folate 9.48 (4.6-18.7ug/L)

P3NP 10.4 HIGH (3.3-9.7ug/L) (Liver test to take methetrexate)

SHGB Normal
Vitamin D 138.9 nmol/L

Serum TSH level 2.58 miU/L
Serum prolactin level 273 (86-324mu/L)

Serum FSH level 9.2 (1.50-12.40IU/L)
Serum LH level 4.9 (1.70-8.60IU/L)

Anti Nuclear antibody Normal

SST test for Cortisol has also come back normal



Your help and advice is greatly appreciated…

Hoping I can find some help and support here for what seems like a dead end situation Ive got myself into…

Started taking propecia for hairloss for 5 years (1mg a day)
Came off propecia after noticing a significant drop in sex drive and ED
During these 5 years I go from top performing sportsman to lazy and overweight and unmotivated
I breeze through university but then this new found fatigue causes me to take the easy options in life and walk away from my chosen career path
I also develop severe psoriasis during this period while on propecia
I literally go from top performing alpha male to rock bottom

I have been off propecia 5 years and somehow managing to exist with all these symptoms and just get by
Then after training in the gym for 3 months before a holiday to Las Vegas I crash majorly
(was taking grenade fat burners twice a day for 3 months during this period)

I now

  • Find it impossible to get up in the mornings my eyes sting and my body is so weak I can barely stand up without assistance
  • Can not remember anything and have no concentration
  • Can not play any sport as I am out of breath instantly and my body is so weak
  • Can not train in the gym as I am then in pain for upto 7 days
  • Have no regular digestive routine and am always constipated
  • Never ever have morning wood
  • Erections are weak and orgasm is almost non existent
  • Testicles / penis have shrunk and always feel like they are trying to go inside
  • Severe depression and feel like I have lost my personality
  • Weight gain in hips arse stomach and face, female body like

Having been to see a private endo he has done the attached tests and also recently and SST for Cortisol which came back normal

He is at a loss and seems completely unaware of any permanent damage caused by Propecia / Finasteride and says maybe I have ME which I feel is a complete cop out

Please can anyone point me in the right direction

I suspect TRT may be the best route to go



Posted the info for you below sir

Let me know your train of thought

And thanks for your input - this forum is giving me some hope as to getting over this!


Don’t get me dancing on duplicate threads, one needs to die.

Keep your case in one thread.


sorry Ksman new user

I dont know how to delete thread but I guess it makes sense to delete this one?

How do I do that ?


Not simple… just do not post to this.