The above...plus crap mood and low energy. For me personally, any imbalance (with the exception of very high T) causes roughly the same subjective symptoms. Crappy mood, low energy, low libido, sexual dysfunction, etc. Joint pain seems to be specific to low-E, for me.
Symptoms are one thing, but you know for a fact that your E2 is too low so I would go off that! I would skip the Adex for a week to let your E2 rebound. Then start again at half the dose. Retest after 6 weeks of this to see where you're at. I'm not a doctor but this is what I did, and it seemed to do the trick. You're at double the "standard" starting dosage for Adex anyway so it's pretty obvious.