T Nation

Long-Term TRT Data?

I’m sure this has been asked, but I think it needs to be asked frequently because there are frequent updates. Anyone have any longitudinal data for test replacement 100-150mg at like 20+ years? Might be useful information to have up for everyone.

There are 11 years of data, but not 20+ years. The conclusion was the benefits outweigh the risks because the data of long term with low-T are even more clear and dire.

https://www.nature.com/articles/s41366-019-0517-7.pdf

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Would those risks also include long term low free-t due to high SHBG?