Thanks to MG and buddaboy. I have read about the desensitization of AR's and believe that holds general truth in all endocrinology. Unbound test is then gobbled up by SHBG and removed. But to what degree or when, who really knows. Wound Masteron or other substance (i.e. herb) help to keep that sensitivity?
As far as my nutritional advice, my research/study background is near the doctoral level in anthropology. Works by Cordain and Eaton (two of the more accomplished anthro's out there) have painted a very clear picture that deficiency/toxicity is the root of most common chronic disease. The credible, non-industry funded, research shows abundant evidence that a paleolithic diet plan is the closest to the perfect diet for human genetics. Its futile to argue that a species that not just survived but thrived on the paleo diet for literally hundreds of thousands of years+ (sans grains and milk and obviously processed shit) should be eating anything remotely resembling the typical western diet.
Anyway, he mostly eats veggies, fruit, lean meat (grass-fed red meat), nuts, seeds, and gets plenty of carbs from starchy root veg and a few servings of grain like oatmeal or sprouted bread, and some cheese. Yes I know grains/dairy are not Paleo approved but I have to be pratical with clients plus I believe as long as it's of the best quality grains and dairy can be consumed in limited quants. He also takes the best molecular forms of omega 3 fatty acids, D3, multi-vitamin/mineral, etc. I also have him on a high performance PWO shake which is a custom blend of whey/casein hydrolisates, high-insulin carbs, BCAA's, etc, etc.
As far as the pathology on heart disease (atherosclerosis), its driven by an inflammatory diet/lifestyle, deficiencies, stress and lack of activity. Genetics are WAY down on the list. On the paleo diet, I do not believe moderate steroid (not long-term, such as a year) use will significantly increase this risk. Cancer I believe might be a different story as chronically elevated sex hormones can increase cancer risk.