[quote]Bill Roberts wrote:
My pharmacist proceeded to tell me it was metabolized in the liver and was therefor not hepatotoxic…which does not make sense in the slightest.
Needless to say I think my pharmacist is not very trustworthy.
Exactly how does it not make sense that simply the fact a substance is metabolized in the liver does not mean it is hepatotoxic?
Almost everything is metabolized in the liver (excluding those things that need no metabolism to be excreted.)
Do you think they are all hepatotoxic?
What a lousy way for the liver to work that would be.
Azithromycin is widely administered and is hardly destroying livers right and left.
Your doctor and pharmacist’s statements that the effect is minimal have a lot more weight and correctness than your theory on the consequences of being metabolized by the liver.
Additionally, if you have not been abusing 17-alkylateds to this point – that is to say, you haven’t been using them for an excessive duration of time nor at an extreme dose – then their adverse effect on the liver is pretty minimal as well. I would not be concerned about the combination for a period of a few days. Only if a person were on the edge of a serious liver problem already would such a thing possibly push them over the edge. If you’re in that position, then stopping the orals for just a few days, as per your plan, isn’t the right plan as you would need to stop them period for quite some time. Or if you’re not in that position, then again your plan of stopping the orals for a few days would not offer advantages. [/quote]
Azithro specifically is hepatotoxic according to what I have read.
Then again so is tylenol, hence my question on how toxic it might be.
I have not been abusing 17aa, but I do run them for the normal length of time, my liver values were good as of the beginning of my run.
If you dont see any obvious problems with it then that makes me feel significantly better.
Thank you for the response Bill.