[quote]swordthrower wrote:
Headhunter wrote:
Actually, there are absolutely no clinical studies which show that cholesterol levels are correlated with risk of heart disease. All the studies which are used to promote statin drugs are inconclusive at best, and most are epidemiological. Lifestyle habits (including a high-refined-carb diet) probably have a lot more impact on your heart disease risk than anything, as you suggest.
But the fact is, pharmaceutical companies can’t make money off of people who eat well and exercise regularly![/quote]
Well unfortunately your there.
Start with the primary studies like MrFit, Framingham and The Seven Countries studies. Secondary studies include 4S, WOSCOP, TNT and HPS. Most of these have been published in The Lancet (not some shitbag journal).
There is indeed a direct correlation between cholesterol and your risk of having a cardiac event. Lowering your cholesterol if you’ve had an event, reduces the risk of a second event. Diabetics have even stronger data. Treat 17 patients witha statin (over 5 years) and prevent one serious cardiac event. Don’t sound like much? Estimate the cost to health insurers (and families), and this is actually cheap treatment.
A reduction of LDL alone, while decreasing relative risk, is not the be-all-and-all. Smoking. genetics and lifestyle also play a role.
The research also concludes thatthere are 7 different LDL size molecules, and the denser molecule is more athrogenic. Lukily, statins reduce all sized LDL and IDL levels, as well as CRP, apoB and increases in HDL.
Yes, there is big money to be made. But guess what? That makes the world go around. It also means these pharmaceutical companies also produce many other medication that most on this board are probably taking.
As for negative stories on any issue - check the quality of journal, and wether it has been peered reviewed. I have published many science articles, and I can tell you, my research wasn’t groundbreaking enough to make The Lancet, or the New England Joiurnal of medicine. But the body evidence definately says that reduce reduce cardiovascular risk and events.