Libido/Arousal Issues from cGMP-Specific Phosphodiesterase Type 5 Overproduction?

I got to thinking, maybe my body just produces too much cGMP-specific phosphodiesterase type 5, the stuff that Viagra and Cialis block.

Is there any research done to show what would cause one to produce too much? Perhaps figuring out WHY one would make too much of the boner killing enzyme would be key in helping with arousal, other than throwing Viagra at the problem.