T Nation

KSman, Need Your Advice


#1

My current protocol: Test Cyp 30mg EOD with 30G 1/2 needle, HCG 250 units SQ EOD. It's test-hcg-test-hcg. 0.25 mg Arimidex 2 times a week. I have used different dosing templates (one time a week IM, split dose two times a week IM, SQ EOD, etc). I have always had a high SHBG no matter what protocol I use but my current EOD has resulted in the highest increase of SHBG. My Thyroid function, and LFTs are always normal. My HCT gets high but I bring it into the normal range with blood donation.

My labs are the following: Total Test LC/MS = 2006 (348-1197 ng/dL), Free Test=32 (7.2-24 pg/ml), DHT 223 (30-85ng/dL), Estradiol 22.9 (7.6-42.6), PSA 0.7 (0.0-4.0ng/ml), SHBG 85.9 (19.3-76.4 nmol/L). Not great sex drive but can get and maintain an erection, increased body hair, low energy, seems like I'm actually loosing muscle mass. Should I decrease frequency but increase mg per injection?


#2

Is 2007 TT a type for 1007?

High SHBG will push your TT up but not that much, and your FT would be lower. Strange.


#3

no. The TT IS REALLY 2006


#4

So your TT is mosty T+SHBG because SHBG is high.

This is not a result of how you inject.


"
SHBG levels increase with estrogenic states (oral contraceptives), pregnancy, hyperthyroidism, cirrhosis, anorexia nervosa, and certain drugs. Long-term calorie restriction of more than 50 percent increases SHBG, while lowering free and total testosterone and estradiol.
"

SHBG is made in the liver. Is there something odd there?


#5

so I dont know what you are saying… No hyperthyroidism, No cirrhosis, no other drugs, No anorexia etc